|
|||||
|
|
| 分子印迹在氟喹诺酮类药物分离中的应用 | |
| 引用本文： | 何丹凤,苏立强,王俊涛.分子印迹在氟喹诺酮类药物分离中的应用[J].高师理科学刊,2008,28(1):65-68. |
| 作者姓名： | 何丹凤 苏立强 王俊涛 |
| 作者单位： | 1. 大庆师范学院,化学化工系,黑龙江,大庆,163712 2. 齐齐哈尔大学,化学与化学工程学院,黑龙江,齐齐哈尔,161006 3. 黑龙江八一农垦大学,文理学院,黑龙江,大庆160039 |
| 摘 要： | 采用本体聚合法,以环丙沙星和沙拉沙星互为模板分子合成了环丙沙星和沙拉沙星分子印迹聚合物,并用高效液相色谱法研究了印迹聚合物的识别性能及作为色谱固定相的分离及影响因素.将制备的分子印迹固定相用于HPLC,该固定相对模板分子有特异性识别能力,达到了预期的分离效果. |
| 关 键 词： | 分子印迹聚合物 高效液相色谱法 环丙沙星 沙拉沙星 |
| 文章编号： | 1007-9831（2008）01-0065-04 |
| 收稿时间： | 2007-09-15 |
| 修稿时间： | 2007年9月15日 |
Application study of separation of fluoroquinolone drugs imprinted polymers |
|
| HE Dan-feng,SU Li-qiang,WANG Jun-tao.Application study of separation of fluoroquinolone drugs imprinted polymers[J].Journal of Science of Teachers＇College and University,2008,28(1):65-68. | |
| Authors: | HE Dan-feng SU Li-qiang WANG Jun-tao |
| Abstract: | The MIP was synthesized with ciprofloxacin or Sarafloxacin as template Using bulk polymerization, and high performance liquid chromatography was employed to study the recognition property and separation and influencing factors as the stationary phase chromatographic of the resulting MIP, and the prepared molecular imprinting stationary phase was used in High Performance Liquid Chromatography, the stationary phase recognition of template elements with a specific identification capability to meet the expected separation effect. |
| Keywords: | molecularly imprinted polymer high performance liquid chromatography CIP SAR |
| 本文献已被 维普 万方数据 等数据库收录！ | |