| N-甲基血卟啉化合物的合成及抗癌性质 |
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| 引用本文： | 金为群,刘玉文,曹锡章,于连香,陈禄,张迎春.N-甲基血卟啉化合物的合成及抗癌性质[J].吉林大学学报(理学版),1998(4). |
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| 作者姓名： | 金为群 刘玉文 曹锡章 于连香 陈禄 张迎春 |
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| 作者单位： | 长春科技大学材料系，吉林大学化学系，白求恩医科大学第三临床医院 |
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| 摘 要： | 合成一种Ｎ－甲基血卟啉，并通过紫外可见光谱、红外光谱和元素分析等手段进行表征．研究它在金属离子存在条件下甲基自由基的性质．经过细胞培养实验证明，该化合物对癌细胞有良好的杀伤作用．对白血病的抑制率可达６３％以上．
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| 关 键 词： | 血卟啉，烷化剂，抗癌作用 |
The Synthesis of N methyl Hematoporphyrin Compound and Its Property of Anticancer |
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| Jin Weiqun.The Synthesis of N methyl Hematoporphyrin Compound and Its Property of Anticancer[J].Journal of Jilin University: Sci Ed,1998(4). |
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| Authors: | Jin Weiqun |
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| Abstract: | N methyl hematoporphyrin was synthesized and characterized by means of UV, IR spectra and elementary analysis. The properties of the free radical, methyl of N methyl hematoporphyrin were studied in the presence of metal ions. The cell culture experiment confirmed that the compound exhibited better damaging effect on cancer cells such as S 180 , Helas and yac. |
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| Keywords: | alkyl containing agent hematoporphyrin anticancer |
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