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折苞斑鸠菊中的黄酮类成分
引用本文:王韵华,王军,马文哲.折苞斑鸠菊中的黄酮类成分[J].中山大学学报(自然科学版),2010,49(2).
作者姓名:王韵华  王军  马文哲
作者单位:1. 中山大学药学院,广东,广州,510006;广东省药品检验所,广东,广州,510180
2. 中山大学药学院,广东,广州,510006
摘    要:用硅胶、反相硅胶、凝胶和薄层色谱等方法从折苞斑鸠菊(Vernonia spirei Gandog)甲醇提取物的乙酸乙酯部分中分离黄酮类成分,得到2个化合物,通过光谱和波谱分析,分别鉴定为:5,7,4’-三羟基-6,3-二甲氧基黄酮(Ⅰ)、5,7,4’-三羟基-6,3-二甲氧基黄酮(Ⅱ)。以上化合物均为首次从该植物中分离得到。

关 键 词:折苞斑鸠菊  黄酮
收稿时间:2009-06-15;

Flavones of Vernonia spirei Gandog
WANG Yunhua,WANG Jun,MA Wenzhe.Flavones of Vernonia spirei Gandog[J].Acta Scientiarum Naturalium Universitatis Sunyatseni,2010,49(2).
Authors:WANG Yunhua  WANG Jun  MA Wenzhe
Institution:WANG Yunhua1,2,WANG Jun1,MA Wenzhe1(1.School of Pharmaceutical Sciences,Sun Yat-sen University,Guangzhou 510006,China,2.Guangdong Institute for Drug Gontrol,Guangzhou 510180,China)
Abstract:The chemical constituents of Vernonia spirei Gandog were studied.The constituents were separated and purified from MeOH extract of the whole plant with column chromatographic methods through silica gel,RP-18 silica gel,Sephadex LH-20,HPLC,and preparative TLC.Their chemical structures were characterized by spectroscopic methods including NMR and EIMS.The result showed that Vernonia spirei Gandog contained two components including 5,7,4'-trihydroxy-6,3'-dimethoxyflavone(Ⅰ),5,3'-dihydroxy-6,7,4'-trimethoxyflavone(Ⅱ).These compounds were obtained from this genus for the first time.
Keywords:Vernonia spirei Gandog  flavones
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