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HCO-3-ATPase activity distribution in rat liver cell fractions prepared by zonal centrifugation.
Authors:K T Izutsu  I A Siegel  E A Smuckler
Abstract:Plasma membrane sheets prepared by zonal centrifugation of a premicrosomal pellet obtained from a rat liver homogenate are devoid of HCO-3-ATPase activity. Since the microsomal fraction is also lacking in this ATPase activity, it can be concluded that the HCO-3-ATPase is not involved in the secretion of HCO-3 into bile.
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