| 水分对头孢唑林钠药效的影响初探 |
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| 引用本文： | 马海燕,范妍红,高宏然,陈学诚. 水分对头孢唑林钠药效的影响初探[J]. 河北科技大学学报, 1995, 0(2) |
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| 作者姓名： | 马海燕 范妍红 高宏然 陈学诚 |
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| 作者单位： | 石家庄市第二制药厂，河北轻化工学院环境工程系 |
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| 摘 要： | 用平衡湿度法测定了头孢唑林钠的临界相对湿度，在２０℃时约为６７％。同时，通过破坏性实验考察了水分对其药效的影响，初步结果表明，水分每增加１％，效价降低约０．５％。据此，提出了分装操作的若干注意事项。
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| 关 键 词： | 头孢唑林钠；平衡湿度法；临界相对湿度；稳定性；效价；破坏性实验 |
Preliminary Study of the Influence of Moisture Content on the Drug Potency of Sodium Cephazolin Powder |
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| Ma Haiyan, Fan Yanhong, Gao Hongran, Chen Xuecheng. Preliminary Study of the Influence of Moisture Content on the Drug Potency of Sodium Cephazolin Powder[J]. Journal of Hebei University of Science and Technology, 1995, 0(2) |
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| Authors: | Ma Haiyan Fan Yanhong Gao Hongran Chen Xuecheng |
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| Affiliation: | Shi jiazhuang Second Pharmaceutical Factory |
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| Abstract: | The authors determine the critical relative humidity of sodium cephazolin powder by equilibrium moisture method, the value is about 67% at 20℃. In addition, we investigate the influence of moisture content on the drug potency Of sodium cephazolin powder by means of the destructive test. The preliminary results show that the drug potency is decreased by 0. 5 % while increasing the moisture content by 1. 0% approximately. Thus we put forward a certain number of notices for separating package operation. |
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| Keywords: | sodium cephazolin equilibrium moisture method critical relative humidity stability potency destructive test |
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