Possible existence of a presynaptic positive feedback mechanism enhancing dopamine transmission in the anterior cingulate cortex of the rat |
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| Authors: | M Beauregard A Ferron L Descarries |
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| Affiliation: | Centre de Recherche en Sciences Neurologiques (Département de Physiologie), Faculté de Médecine, Université de Montréal, Québec, Canada. |
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| Abstract: | ![]()
A series of microiontophoretic and VTA stimulation experiments, conducted in intact, GBR-12909-treated, alpha-methylparatyrosine-depleted or 6-hydroxydopamine-denervated rats, provide suggestive evidence for the existence of a presynaptic, positive feedback mechanism triggered by dopamine reuptake and favoring the release of this transmitter in the anterior cingulate cortex. |
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