植物根尖分生组织干细胞调控模式

静止中心(QC)形成和干细胞区特化是植物根尖分生组织确立的标志。静止中心位于根尖分生组织中心,干细胞围绕在静止中心细胞周围。依赖于生长素的PLT途径和不依赖于生长素的SCR/SHR途径共同发挥维持静止中心细胞稳定的作用。静止中心和干细胞区的柱干细胞之间存在类似于WUS/CLV3的WOX5/ACR4/CLE40的反馈抑制调节途径,该调节途径维持着静止中心细胞和柱干细胞之间的平衡。静止中心和其他类型干细胞之间也可能存在类似的反馈抑制调节途径。生长素、细胞分裂素、赤霉素等植物激素信号在根干细胞功能发挥方面也起到重要作用,与各种基因一起组成根分生组织干细胞调控网络。

The regulatory pattern of stem cell in root apical meristem

The root apical meristem establishing mark is the formation of quiescent center(QC) and the specialization of stem cell in the plant.There are four quiescent center cells in the center of root apical meristem with stem cells around them.Both auxin-dependent PLT pathway and auxin-independent SCR/SHR pathway together play an important role in the stabilization of quiescent center.There is a WOX5/ACR4/CLE40 feedback regulation between quiescent center cells and columella stem cells that is similar to the WUS/CLV3 in the stem apical meristem.The balance between quiescent center cells and columella stem cells is maintained by the WOX5/ACR4/CLE40 feedback pathway.There may be some similar pathway between other types of stem cells and quiescent center cells.The signal of auxin,cytokinin,gibberellin and other phytohormone also play an important role in the root apical meristem.These signals and some kinds of gene constitute regulation networks that regulate the root meristem apical stem cell niche.