| Defensin抗菌肽的序列特性分析 |
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| 引用本文： | 孙雁霞,邬晓勇,何钢,宋芹,王跃华.Defensin抗菌肽的序列特性分析[J].成都大学学报(自然科学版),2010,29(2):101-103. |
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| 作者姓名： | 孙雁霞 邬晓勇 何钢 宋芹 王跃华 |
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| 作者单位： | 成都大学,药用微生物资源重点实验室,四川,成都,610106;成都大学,药用微生物资源重点实验室,四川,成都,610106;成都大学,药用微生物资源重点实验室,四川,成都,610106;成都大学,药用微生物资源重点实验室,四川,成都,610106;成都大学,药用微生物资源重点实验室,四川,成都,610106 |
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| 摘 要： | 对defensin抗菌肽进行了生物信息学分析.一级结构表明其具有典型的昆虫防御素特征.二级结构分析表明defensin抗菌肽中主要的结构元件为α-螺旋,但有例外.信号肽及导肽分析结果显示defensin抗菌肽均属于分泌型蛋白.通过对不同物种defensin抗菌肽的分析结果表明,非阳离子抗菌肽的作用机制可能是疏水作用力起主导作用或者是对细菌胞内酶结构与功能、对细菌胞内信号转导的影响有关.
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| 关 键 词： | defensin类抗菌肽 序列特性 作用机制 |
Sequence Characteristic Analysis of Defensin Antimicrobial Peptides |
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| SUN Yanxia,WU Xiaoyong,HE Gang,SONG Qin,WANG Yuehua.Sequence Characteristic Analysis of Defensin Antimicrobial Peptides[J].Journal of Chengdu University (Natural Science),2010,29(2):101-103. |
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| Authors: | SUN Yanxia WU Xiaoyong HE Gang SONG Qin WANG Yuehua |
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| Institution: | SUN Yanxia,WU Xiaoyong,HE Gang,SONG Qin,WANG Yuehua(Key Laboratory of Medical Microbial Resources,Chengdu University,Chengdu 610106,China) |
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| Abstract: | Defensin antimicrobial peptides were analyzed by bioinformatics tools.Primary structure shows that the defensin has typical characteristics of insect defense.Secondary structure analysis shows that the main defensin antimicrobial peptides are alpha helix structure components,but there is an exception.The signal and target peptide analysis shows that defensin antimicrobial peptides belong to secrete protein.After the analysis of different species of defensin antimicrobial peptides,the results show that the m... |
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| Keywords: | defensin antimicrobial peptides sequence characteristics mechanism |
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