| 1-正丁基环己醇实验室合成 |
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| 引用本文： | 谢祥林,曾佑林,殷懿.1-正丁基环己醇实验室合成[J].吉首大学学报(自然科学版),2010,31(6):90-92. |
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| 作者姓名： | 谢祥林 曾佑林 殷懿 |
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| 作者单位： | （湖南师范大学化学化工学院，湖南 长沙 410081） |
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| 基金项目： | 湖南省教育厅科学研究项目，湖南师范大学教学改革研究项目 |
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| 摘 要： | 设计了1-溴正丁烷与金属镁反应制备格氏试剂，并将其与环己酮反应合成1-正丁基环己醇的实验室合成方案,探讨了金属镁预处理、格氏试剂与环已酮反应时间等实验条件对产率的影响.实验结果表明:金属镁预处理与否对产率的影响不大，格氏试剂与环已酮反应时间需50 min，产率约为50.0%，完成整个实验约需5 h.
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| 关 键 词： | 1-正丁基环己醇 格氏试剂 环已酮 1-溴正丁烷 合成 |
Laboratory Synthesis of 1-n-Butylcyclohexanol |
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| XIE Xiang-lin,ZENG You-lin,YIN Yi.Laboratory Synthesis of 1-n-Butylcyclohexanol[J].Journal of Jishou University(Natural Science Edition),2010,31(6):90-92. |
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| Authors: | XIE Xiang-lin ZENG You-lin YIN Yi |
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| Institution: | (College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China) |
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| Abstract: | Laboratory synthesis of 1-n-butylcyclohexanol was designed. The detail procedure was that Grignard reagent was prepared by 1-butane bromide reaction with Magnesium, and then 1-n-butyl-cyclohexanol was synthesized by the reaction of Grignard reagent prepared with cyclohexanone. The reaction conditions were investigated. The results show that the pretreatment of rod magnesium has little effect on the productivity, the optical reaction time of the Grignard reaction is 50 min with the corresponding yield being approximately 50.0 %，and this experiment can be done in 5 h. |
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| Keywords: | 1-n-butylcyclohexanol Grignard reagent cyclohexanone n-butyl bromide |
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