| 药物动力学房室模型的改进 |
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| 引用本文： | 曾文艺,孙晓颖.药物动力学房室模型的改进[J].北京师范大学学报(自然科学版),2012,48(1):6-10. |
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| 作者姓名： | 曾文艺 孙晓颖 |
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| 作者单位： | 北京师范大学信息科学与技术学院,1００８７５,北京 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 运用数学建模的方法，建立了一个改进的药物动力学的房室模型，利用临床数据和剩余浓度法对模型的参数进行估计，并验证了该模型的可行性及应用性．
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| 关 键 词： | 房室模型 肾的重吸收 剩余浓度法 |
IMPROVED COMPARTMENTAL MODEL ON PHARMACOKINETICS |
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| ZENG Wenyi,SUN Xiaoying.IMPROVED COMPARTMENTAL MODEL ON PHARMACOKINETICS[J].Journal of Beijing Normal University(Natural Science),2012,48(1):6-10. |
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| Authors: | ZENG Wenyi SUN Xiaoying |
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| Institution: | (College of Information Science and Technology,Beijing Normal University,100875,Beijing,China) |
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| Abstract: | An improved compartmental model for pharmacokinetics was introduced by mathematical modeling.Model parameters were estimated from clinical data and rest concentration method.The model was tested by one numerical sample to illustrate that the proposed model was reasonable. |
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| Keywords: | compartmental model kidney reabsorption rest concentration method |
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