Dopamine-induced relaxation in human pulmonary arteries |
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Authors: | M Yamauchi Y Kobayashi K Hattori K Yamada A Nakase |
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Affiliation: | Department of Pharmacology, Shimane Medical University, Japan. |
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Abstract: | Dose-dependent relaxations were induced by dopamine in human pulmonary arteries that had been contracted with prostaglandin F2 alpha without alpha-adrenergic blocking agents. The dopamine-induced relaxation was inhibited by haloperidol and fluphenazine, but not by domperidone, suggesting that this relaxation was mediated via DA1 receptors. |
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