Conformation and local anesthetic activity of carbanilates |
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| Authors: | L Bene? S ?tolc V Bauer M Tichý |
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| Institution: | (1) Center of Physiological Sciences, Institute of Experimental Pharmacology, Slovak Academy of Sciences, CS-842 16 Bratislava, (Czechoslovakia);(2) Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, CS-166 10 Prague, (Czechoslovakia) |
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| Abstract: | Summary The influence of spatial configuration on intensity, onset, and duration of anesthetic effect has been observed in some carbanilate local anesthetics of fixed conformation. Synthesis of the carbanilates is described. |
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