| 瑞香素及其铜(Ⅱ)、锌(Ⅱ)配合物对超氧自由基的清除作用 |
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| 引用本文： | 廖莉玲,孙作民,房喻,卢秋文.瑞香素及其铜(Ⅱ)、锌(Ⅱ)配合物对超氧自由基的清除作用[J].贵州师范大学学报(自然科学版),1992(4). |
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| 作者姓名： | 廖莉玲 孙作民 房喻 卢秋文 |
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| 作者单位： | 贵州师大化学系，陕西师大化学系，陕西师大化学系，陕西师大化学系 贵阳 550001，西安 710062，西安 710062，西安 710062 |
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| 摘 要： | 本文以健康人血红细胞及细胞膜为实验材料,利用核黄素-蛋氨酸光照体系产生O_D~-,考察了瑞香素及其铜(Ⅱ)、锌(Ⅱ)配合物时O_2~-的清除作用。结果表明:瑞香素及其铜(Ⅱ)、锌(Ⅱ)配合物对O_2~-都有明显清除作用,以钢(Ⅱ)配合物活性最高;O_2~-可使Hb氧化,使膜中过氧化脂质含量增加,SOD、瑞香素及其铜(Ⅱ)、锌(Ⅱ)配合物对此均有一定的抑制作用,其中以SOD活性最高。
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| 关 键 词： | 瑞香素 铜(Ⅱ) 锌(Ⅱ) 超氧自由基阴离子(O_2~-) 脂质过氧化 |
SCAVENGING EFFECTS OF DAPHNETIN AND ITS COPPER(Ⅱ) ZINC(Ⅱ) COMPLEXES ON SUPEROXIDE RADICAL |
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| Liao Liling.SCAVENGING EFFECTS OF DAPHNETIN AND ITS COPPER(Ⅱ) ZINC(Ⅱ) COMPLEXES ON SUPEROXIDE RADICAL[J].Journal of Guizhou Normal University(Natural Sciences),1992(4). |
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| Authors: | Liao Liling |
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| Abstract: | The scavenging effects of daphnetin and its Cu(Ⅱ) Zn(Ⅱ) complexes on superoxide radical(O_2~-)generated through riboflavine-methionin photo-red- uction were investigated with human red blood cell (RBC) and RBC membranes as the experimental materials. The results indicate that,daphnetin and its Cu (Ⅱ) , Zn(Ⅱ) complexes have significant scavenging effects on O_2~- and can inhibit oxidation of hemoglobin (Hb) and lipid peroxidation of RBC membranes induced by O_2~- just as SOD. |
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| Keywords: | Daphnetin Copper(Ⅱ) Zinc(Ⅱ) Superoxide Radical Lipid Peroxidation |
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