The control of contraction activation by the membrane potential

Summary Force measurements under voltage-clamp control were performed in short toe muscles of the frog. The results show a) that the activation of force development and its repriming process can at least qualitatively be correlated to charge movement kinetics; b) that caffeine improves EC coupling by potentiating the potential dependent activation process.This work was supported by DFG (SFB 114 Bionach) and DAAD.