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Effect of des-Tyr1-gamma-endorphin on serotonin metabolism in rat brain regions |
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| Authors: | M Kurachi D H Versteeg J M Van Ree H G Westernberg H M Van Praag |
| Abstract: | Intracerebroventricular (i.c.v.) administration of des-Tyr1-gamma-endorphin (0.1 and 1.0 microgram) caused a decrease of the serotonin (5-HT) concentration of the hippocampus. The concentration of 5-HIAA and the pargyline-induced alterations in 5-HT and 5-HIAA were not affected. No effects were noticed in other brain regions. |
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