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肝再生细胞周期中增殖启动及其调控研究
引用本文:刘晓萌,李玉昌,徐存拴.肝再生细胞周期中增殖启动及其调控研究[J].河南师范大学学报(自然科学版),2004,32(4):92-95.
作者姓名:刘晓萌  李玉昌  徐存拴
作者单位:河南师范大学,生命科学学院,省部共建细胞分化调控国家重点实验室培育基地,河南,新乡,453007
基金项目:河南省重大科技攻关项目(0122031900),河南省青年骨干教师资助项目(521635)
摘    要:肝再生细胞周期中增殖启动及其调控是一个研究热点,到底是何种因素及其涉及到的信号传导途径诱导了Go期肝细胞的启动仍然是一个谜.本文主要以JNK、TNF-α、IL-6、一氧化氮等因子及其可能参与的调控途径综述了肝再生启动的一些最新研究进展.

关 键 词:肝再生  增殖启动  TNF-α  IL-6  细胞周期
文章编号:1000-2367(2004)04-0092-04
修稿时间:2004年6月10日

Study on proliferation initiation and its regulation in cell cycle during hepatic regeneration
LIU Xiao-meng,LI Yu-chang,XU Cun-shuanbortory of the Cell Differentiation and Regulation Built by Province and Ministry,Xinxiang ,China.Study on proliferation initiation and its regulation in cell cycle during hepatic regeneration[J].Journal of Henan Normal University(Natural Science),2004,32(4):92-95.
Authors:LIU Xiao-meng  LI Yu-chang  XU Cun-shuanbortory of the Cell Differentiation and Regulation Built by Province and Ministry  Xinxiang  China
Institution:LIU Xiao-meng,LI Yu-chang,XU Cun-shuanbortory of the Cell Differentiation and Regulation Built by Province and Ministry,Xinxiang 453007,China)
Abstract:The trigger of hepatic proliferation initiation and its regulation in cell cycle during liver regeneration has been the subject of intense investigation. It is still an enigma which factors and their involved signal pathways cause G0 hepatocyte to initiate. In this article, JNK, TNF-α,IL-6 ,NO et al factors and their probably regulation pathways are reviewed to show some advanced study.
Keywords:hepatic regeneration  proliferation initiation  TNF-α  IL-6  cell cycle
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