小儿肺炎支原体肺炎126例临床分析

目的探讨小儿肺炎支原体肺炎的临床特点和诊治方法。方法回顾性分析我科室2001年3月-2007年3月间126例肺炎支原体肺炎的临床特点、实验室检查、X线特点及应用阿奇霉素序贯治疗的疗效。结果小儿肺炎支原体肺炎临床表现以不规则发热，顽固性剧烈咳嗽为主，伴喘憋，肺部体征少。X线表现多为单侧病变，病变右下肺多于左肺。肺炎支原体肺炎可发生肺外脏器受损。应用阿奇霉素序贯治疗可获痊愈。肺外疾病需要对症处理，有时需应用激素。结论肺炎支原体肺炎临床症状较重，但体征较轻微，X线胸片阴影明显，是本病的特点。对有上述表现的肺炎患儿应及时寻找肺炎支原体感染的证据，大环内酯类抗生素治疗有效，尤其是阿奇霉素序贯治疗肺炎支原体肺炎疗效可靠，且副作用少，可做为治疗肺炎支原体肺炎首选用药。

Clinical analysis of 126 cases of children with MPP

Objective: To investigate clinical features and treatment of mycoplasmal pneumoniae pneumonia.Methods: Retrospective analysis of the clinical features,results of laboratory examination,characteristics of X-ray and curative effects of macrolides drugs on 126 patients. Results: Mycoplasmal pneumoniae pneumonia has the features of irregular fever,severe refractory cough and wheeze,but few pulmonary signs. Azithromycin follow-up therapy is usually applied for treating this disease. Extrapulmonary complication need treatment accordingly,sometimes glucocorticoid may help. Conclusion: Mycoplasmal pneumonia characterized as severe clinical symptoms with little objective signs and obvious shadows on X-ray films. When meeting these symptoms ,we ought to promptly search for evidences of mycoplasma pneumoniae infection. Macrolide antibiotics,especially azithromycin,were effective with few side reactions in the treatment of mycoplasmal pneumonia,which could act as a preferred drug for treating mycoplasmal pneumonia.