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| 作为生物探针的噻唑橙类化合物的合成及光谱性质研究 | |
| 引用本文： | 季维,费学宁,杨少斌.作为生物探针的噻唑橙类化合物的合成及光谱性质研究[J].天津理工大学学报,2007,23(3):8-12. |
| 作者姓名： | 季维 费学宁 杨少斌 |
| 作者单位： | 1. 天津理工大学,化学化工学院,天津,300191 2. 天津城市建设学院,科研处,天津,300384 3. 西安航空技术高等专科学校,西安,710077 |
| 摘 要： | 以6-甲基-2-氨基苯并噻唑为原料,合成了噻唑橙染料的一个衍生物,并比较了它与其他两种噻唑橙类染料的光谱性质,讨论了取代基的引入对于染料光谱性质的影响.结果表明,与噻唑橙相比,在分子中引入甲基后,染料的最大吸收波长发生红移;与蛋白结合后最大吸收波长红移,荧光最大波长蓝移. |
| 关 键 词： | 生物探针 6-甲基-2-氨基苯并噻唑 噻唑橙 光谱性质 |
| 文章编号： | 1673-095X（2007）03-0008-05 |
| 收稿时间： | 2006-11-20 |
| 修稿时间： | 2006-11-20 |
Synthesis and spectral properties of thiazole orange compounds as biological probes |
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| JI Wei,FEI Xue-ning,YANG Shao-bin.Synthesis and spectral properties of thiazole orange compounds as biological probes[J].Journal of Tianjin University of Technology,2007,23(3):8-12. | |
| Authors: | JI Wei FEI Xue-ning YANG Shao-bin |
| Abstract: | A derivative of the dye thiazole orange was synthesized using 6-methyl-2-aminobenzothiazole as a raw material.Spectral properties of this compound were compared to the two dyes prepared in our previous work.The Influence of introducing groups on the spectrum of the dye was discussed.Results show that,as compared with thiazole orange,the introduction of methyl to the molecule makes bathochromical shift of absorption maximum of the dye.In addition,binding of BSA protein with the molecule leads to the bathochromical shift of absorption maximum and hypsochromical shift of fluorescent maximum of the dye. |
| Keywords: | biological probe 6-methyl-2-aminobenzothiazole thiazole orange spectral properties |
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