| 肉桂酰杯[4]芳烃的合成及清除自由基活性 |
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| 引用本文： | 蒋海英,林文俊,张晓梅. 肉桂酰杯[4]芳烃的合成及清除自由基活性[J]. 安徽理工大学学报(自然科学版), 2009, 29(1) |
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| 作者姓名： | 蒋海英 林文俊 张晓梅 |
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| 作者单位： | 安徽理工大学化学工程学院,安徽,淮南,232001 |
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| 摘 要： | 杯[4]芳烃经醚化、氨解得到了含酰肼基团的中间体3，在PEG-400存在下，肉桂酰氯与3反应获得了含肉桂酰基的杯[4]芳烃衍生物4；4-经基肉桂酸与氯甲酸乙酯形成的混合酐与3反应，得到了相应的化合物5。用^1H NMR，^13C NMR及IR对4，5进行了结构表征，用MS对4进行了结构确证。DPPH·法测定4，5清除有机自由基活性的结果表明，4，5的自由基清除率约为19％，比杯[4]芳烃母体及肉桂酸都有所提高。
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| 关 键 词： | 肉桂酰杯[4]芳烃衍生物 合成 自由基清除活性 |
Study on Synthesis of Cinnamyl Calix[4] Arene Derivatives and Their Free Radical Activity Elimination |
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| JIANG Hai-ying,LIN Wen-jun,ZOANO Xiao-mei. Study on Synthesis of Cinnamyl Calix[4] Arene Derivatives and Their Free Radical Activity Elimination[J]. Journal of Anhui University of Science and Technology:Natural Science, 2009, 29(1) |
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| Authors: | JIANG Hai-ying LIN Wen-jun ZOANO Xiao-mei |
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| Affiliation: | School of Chemical Engineering;Anhui University of Science and Technology;Huainan Anhui 232001;China |
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| Abstract: | Cinnamyl calix[4] arene derivative was synthesized by reaction of cinnamonyl chloride with intermediate 3 containing hydrazide radical group generated by etherification and ammonolysis of calix[4]arene with present of PEG-400.Compond 5 was produced by reaction of ammonolysis 3 with mixed anhydride generated by reaction of 4-hydroxy cinnamic acid with ethyl chlorocarbonate.The structures of 4,5 were characterized by 1 H NMR,13C NMR and IR,and 4 by MS also.The efficiency of free radical elimination of 4,5 wit... |
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| Keywords: | cinnamyl callix[4]arene derivatives synthesis free radical activity elimination |
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