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“保肺泰”对C_(57)BL/_6J荷瘤小鼠及化疗荷瘤小鼠NK细胞活性的影响
引用本文:李兴琴,徐增年,周俊琴. “保肺泰”对C_(57)BL/_6J荷瘤小鼠及化疗荷瘤小鼠NK细胞活性的影响[J]. 实验动物科学, 2000, 0(1)
作者姓名:李兴琴  徐增年  周俊琴
作者单位:河北省医学科学院!石家庄050021(李兴琴),河北医科大学实验动物学部(徐增年),河北医科大学中医学院(周俊琴)
基金项目:河北省科委资助! (No .982 76191D)
摘    要:以Lewis肺癌细胞株接种C57BL/6J纯系小鼠造成荷瘤模型,观察中药复方保肺泰对荷瘤小鼠及其化疗后NK细胞活性的影响。结果显示,保肺泰组与荷瘤对照组比较、保肺泰 化疗组与化疗组比较,NK细胞活性均有明显升高(P<0.05)。提示保肺泰可能通过提高机体的免疫力增强抗肿瘤效果。

关 键 词:Lewis肺癌  化疗  保肺泰  NK细胞

The Effect of BaoFeiTai on the Natural Killer Cells Activites with Lewis Lung Cancer Bearing Mice and its Chemotherapy
Li Xingqin Xu Zengnian Zhou Zunqin Hebei Academy of Medical Science. The Effect of BaoFeiTai on the Natural Killer Cells Activites with Lewis Lung Cancer Bearing Mice and its Chemotherapy[J]. Laboratory Animal Science, 2000, 0(1)
Authors:Li Xingqin Xu Zengnian Zhou Zunqin Hebei Academy of Medical Science
Affiliation:Shijiazhuang 050021
Abstract:In this experiment, the effect of BaoFeiTai(BFT) was observed on the Natural Killer cells (NK) activities with Lewis lung cancer bearing mice and its chemotherapy. The results of the experiment showed that NK cells activities increased both in BFT group and in BFT chemotherapy group obviously, as compared with the control group and with chemotherapy group (%P%<0.05) respectively. It suggested that the inhibitory effect of BFT on Lewis lung cancer cells might be achieved by way of strengthening the cellar immune function of the mice.
Keywords:Lung cancer Chemotherapy BaoFeiTai Natural killer cells
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