| Risk Factors of Cervical Carcinoma and Countermeasures against Them in Mountainous Area of Wufeng County ， China |
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| 引用本文： | TAO Ning ,WU Xu-feng ,QIU Xiao-ping ,ZHAO Min ,TAN Yun ,WU Xin-xing . Institute of Virology,Medical School,Wuhan University,Wuhan ,Hubei,China, . Department of Oncology,Zhongnan Hospital,Wuhan University,Wuhan ,Hubei,China.Risk Factors of Cervical Carcinoma and Countermeasures against Them in Mountainous Area of Wufeng County ， China[J].武汉大学学报：自然科学英文版,2005,10(4):759-766. |
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| 作者姓名： | TAO Ning WU Xu-feng QIU Xiao-ping ZHAO Min TAN Yun WU Xin-xing . Institute of Virology Medical School Wuhan University Wuhan Hubei China . |
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| 作者单位： | TAO Ning 1，WU Xu-feng 2，QIU Xiao-ping 1，ZHAO Min 1，TAN Yun 1，WU Xin-xing 1 1. Institute of Virology，Medical School，Wuhan University，Wuhan 430071，Hubei，China; 2. Department of Oncology，Zhongnan Hospital，Wuhan University，Wuhan 430071，Hubei，China |
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| 摘 要： | 0Introduction Cervicalcarcinomaisoneofprevalentmalignancy,itisthesecondmostcommoncancerofwomenintheworld wide(thefirstisbreast cancer).Itisestimatedthatthereare450000newcasesinworldeveryyear,ofwhich80%arein developingcountries.Thereare135000newcasesinChin…
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| 关 键 词： | 子宫颈癌 人类乳头状瘤病毒 HPV 危险因素 治疗方法 |
| 收稿时间： | 2 January 2005 |
Risk factors of cervical carcinoma and countermeasures against them in mountainous area of Wufeng county, China |
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| Tao Ning,Wu Xu-feng,Qiu Xiao-ping,Zhao Min,Tan Yun,Wu Xin-xing.Risk factors of cervical carcinoma and countermeasures against them in mountainous area of Wufeng county, China[J].Wuhan University Journal of Natural Sciences,2005,10(4):759-766. |
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| Authors: | Tao Ning Wu Xu-feng Qiu Xiao-ping Zhao Min Tan Yun Wu Xin-xing |
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| Institution: | (1) Institute of Virology, Medical School, Wuhan University, 430071 Wuhan, Hubei, China;(2) Department of Oncology, Zhongnan Hospital, Wuhan University, 430071 Wuhan, Hubei, China |
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| Abstract: | Cases (n=44) with squamous cell cervical cancer (SCCA) and age-matched healthy controls (n=176) were analyzed. Significant difference due to human papillomavirus (HPV) infection, ages at the first marriage, ages at the first sexual intercourse, ages at the first birth given to baby, number of gravidities, number of deliveries, Body Mass Index (BMI), education level of women and their husbands (p< 0.05) was observed. According to multivariate logistic regression analysis, four factors have entered the model (p<0.05), including HPV infection OR (odds ratio)= 26.13, 95%CI (confidence interval)=9.40-72.60], education level of women (OR= 0.41, 95%CI=0.21-0.79), education level of spouses (OR=0.45, 95%CI=0.22- 0.94), BMI (OR= 0.73, 95%CI=0.57-0.93). Moreover, HPV infection is relative to education level of women (r=-0.14), and their spouses (r=-0.21), age at the first marriage (r=-0.20), age at the first birth given to baby (r= -0.20) and BMI (r=-0.15). |
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| Keywords: | cervical carcinoma human papillomavirus (HPV) risk factor |
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