化学计量学方法用于蛤青注射色谱数据重叠峰的分辨

固定窗口因子分析-直观推导演进投影法被用来将中药色谱-光谱二维数据中重叠峰的部分解析为纯组分色谱曲线和纯组分光谱曲线。在本文中,这种方法都被用来解析复方蛤青注射液色谱-光谱数据中重叠现象非常严重的一部分组分簇。通过对该方法结果的分析,提出了一种改进的新方法--扣除数量级固定窗口因子分析。

Analysis of the compound Haqing injection with hyphenated chromatography and chemometric resolution

Sectional moving window factor analysis(SMWFA)-heuristic evolving latent projection(HELP),are used to resolve the overlapped two-dimensional chromatogram-spectrum data of the Traditional Chinese Medicine into estimated pure component chromatograms and spectrum profiles.In this work,the method was used to resolve a heavily overlapped components cluster of the compound Haqing injection.On the basis of results of the method,an improved deducted order of magnimde of the fixed size moving window evolving factor analysis(DOMFSMWFA)procedure was proposed and applied in the resolution of the compound Haqing injection,and the satisfactory results were obtained.