| 用细胞遗传学方法研究生化灭鼠剂对哺乳动物体细胞的致突变性 |
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| 引用本文： | 杨志荣,刘世贵,朱文,伍铁桥,黄时海.用细胞遗传学方法研究生化灭鼠剂对哺乳动物体细胞的致突变性[J].四川大学学报(自然科学版),1996(5). |
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| 作者姓名： | 杨志荣 刘世贵 朱文 伍铁桥 黄时海 |
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| 作者单位： | 草原生防工程国家专业实验室 |
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| 摘 要： | 经人外周血淋巴细胞姊妹染色单体互换、小鼠骨髓细胞的染色体畸变分析，以及致哺乳动物的嗜多染红细胞的微核发生试验，研究了不同性质的生化灭鼠剂对人和小鼠体细胞的致突变性．结果表明，无论生化灭鼠剂是否具生理毒性，对人和小白鼠体细胞均不具致突变性
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| 关 键 词： | 姊妹染色单体互换，微核，染色体畸变，生化灭鼠剂 |
TESTS OF MUTAGENICITY OF BIOCHEMICAL RODENTICIDE TO VERTEBRATE SOMATIC CELLS BY MEANS OF CYTOGENETIC METHODS |
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| Yang,Zhirong Liu,Shigui Zhu,Wen Wu,Tieqiao Huang,Shihai.TESTS OF MUTAGENICITY OF BIOCHEMICAL RODENTICIDE TO VERTEBRATE SOMATIC CELLS BY MEANS OF CYTOGENETIC METHODS[J].Journal of Sichuan University (Natural Science Edition),1996(5). |
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| Authors: | Yang Zhirong Liu Shigui Zhu Wen Wu Tieqiao Huang Shihai |
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| Institution: | National Loboratory of Grassland Biological Control |
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| Abstract: | The mutagenicity of vertebrate somatic cells effected by biochemical rodentacide was examined by the methods of chromosomal aberration of mice marrom cells and PCE micronuclei formation.The results show that biochemical rodenticide have no mutant effects on vertebrate somatic cells. |
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| Keywords: | sister chromatid exchange micronuclei chromosomal aberration biochemical rodenticide |
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