磁控减肥胶囊反应机理及结构研究

针对肥胖且不宜剧烈运动人群的减肥需求，提出了一种可以在胃内完成充放气过程的磁控减肥胶囊模型。胶囊内通过酸碱盐反应使气囊充气，充气后的气囊在胃中通过占据胃内容积以达到减重的目的。该化学反应的发生由内部小磁铁控制，并且小磁铁的驱动可由外部磁体控制；在治疗结束后通过外部磁铁使气囊放气，胶囊可从消化道自然排出。结合化学实验确定了采用一水合柠檬酸饱和溶液与碳酸氢钠粉末反应的方案，并将溶液体积控制在2 mL内；通过COMSOL Multiphysics软件对磁铁模型进行有限元仿真分析，估算了胶囊外部磁铁的体积。研究结果揭示了磁控减肥胶囊的反应机理，也证明了该胶囊结构模型的可行性。

Reaction mechanism and structure of magnetic control slimming capsule

For obese people who were not suitable for strenuous exercise, a magnetic control slimming capsule model that could complete the process of inflating and deflating in the stomach was proposed. The capsule was inflated by the acid-base salt reaction, and the inflated balloon occupied the internal gastric volume in the stomach to achieve the purpose of weight loss. The occurrence of the chemical reaction was controlled by small magnets inside, and the driving of small magnets could be controlled by an external magnet. After the treatment was over, the balloon was deflated by the external magnet and the capsule could be discharged naturally from the digestive tract. Combined with chemical experiments, the reaction scheme was determined as a saturated solution of citric acid monohydrate reacting with sodium bicarbonate powder, and the volume of the solution was controlled at 2 mL. The finite element simulation analysis of the magnet model was carried out by COMSOL Multiphysics software, and the volume of the magnet outside the capsule was estimated. The results revealed the reaction mechanism of the proposed capsule structure model and proved its feasibility.