美能针配合化疗治疗妇科肿瘤的临床观察

目的观察美能注射液联合化疗治疗恶性肿瘤的疗效和毒副反应。方法将患者分为美能联合化疗组（治疗组）和单纯化疗组（对照组）进行疗效和毒副反应比较，统计方法以卡方检验。结果治疗组有效率58．3％（35／60），对照组有效率40．0％（24／60），两组比较有显著差异（P〈0．05）。治疗组无肝功能损害，消化道反应占30．0％（18／60）程度轻，对照组肝功能损害占38.3％（23／60），消化道反应占43．3％（26／60）程度重。结论美能注射液联合化疗治疗恶性肿瘤，提高了疗效，预防药物性肝损害的发生，并减轻恶心、呕吐、乏力、食欲下降等其它消化道毒副反应的程度，提高患者的生存质量，值得推广。

Clincal oberservatian of strong neominophagen C injection in combination with chemotherapy in the treatment of gynecological tumors

Objective To observe the efficacy and toxic reactions of strong neominophagen C injection in combination with chemotherapy in the treatment of gynecological tumors. Methods The patients were assigned to receive chemotherapy in combination with strong neominophagen C injection （treatment group） or chemotherapy alone （control group）. The efficacy and adverse reactions of two groups were compared by chi-square test. Results The overall response rate （CR ＋ PR） were 58.3% （35/60）in the treatment group and 40.0% （24/60） in the control group, and significant differences were noted between two groups （ P 〈 0.05）. None of the patients in the treatment group were noted of hepatic lesion, but 38.3% （23/60） in the control group were noted of hepatic lesion ; and the gastrointestinal reactions in the treatment group were also less severe than in the control group, which were noted in 30. 0 % （18/60） in the treatment group and 43.3% （26/60） in the control group. Conclusion Strong neominophagen C injection plus chemotherapy can not only improve the curative effect, prevent drug -induced hepatic lesion, alleviate the gastrointestinal toxic reactions such as nausea, vomiting, anorexia and weakness, but also improve the life quality of patients withintermediate and end - stage gynecological tumors, which thus deserving to be widely used.