Studies on the etiology of the experimental neuropathy from industrial adhesive (glues)

Summary Chickens treated by paintbrushing with glue distillate (used in shoe industries), hydrocarbon mixture and TOCP in hexane, developed paralysis (4/5); in these, we have demonstrated a diffuse degeneration of the myelinic sheath of the peripheral and central neurites. Besides TOCP, cyclohexane (because of its higher concentration in the glue distillate and in the hydrocarbon mixture) may be indicated as responsible for occupational neuropathy.Acknowledgments. The authors thank Prof. G. Azzali, Director of the Institute of Human Anatomy University of Parma (Italy), for his interpretations of microscopic ultrastructural aspects.Istituto di Anatomia Umana Normale.Istituto di Clinica Neurologica.Istituto di Chimica Organica.