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The agonist of the protease-activated receptor-1 (PAR1) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human vascular smooth muscle cells
Authors:T Arisato  K P Sarker  K Kawahara  M Nakata  T Hashiguchi  M Osame  I Kitajima  I Maruyama
Institution:(1) Department of Laboratory and Molecular Medicine, Faculty of Medicine, Kagoshima University, Kagoshima, Japan;(2) Department of Cell Biology and Anatomy, The University of Calgary, Faculty of Medicine, 3330 Hospital Dr., NW, 383 Heritage Medical Research Building, T2N 4N1, Calgary, Alberta, Canada;(3) Third Department of Internal Medicine, Faculty of Medicine, Kagoshima University, Kagoshima, Japan;(4) Department of Laboratory Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan
Abstract:
Keywords:Thrombin  HVSM cell  PAR1  Ca2+  p44/42  VEGF
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