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细菌群体感应机制与动植物病原菌的致病力
引用本文:宋水山,赵占良,王立杰,白志奇.细菌群体感应机制与动植物病原菌的致病力[J].河北省科学院学报,2003,20(2):124-128.
作者姓名:宋水山  赵占良  王立杰  白志奇
作者单位:1. 河北省科学院生物研究所,石家庄,050051
2. 河北省隆尧县动物检疫站,隆尧,055350
摘    要:N 酰基高丝氨酸内酯 (AHLs)作为信号分子介导的细菌群体感应机制参与许多生物学功能的调节 ,当侵染动植物寄主组织的病原菌繁殖到一定量时 ,细菌本身产生的AHLs积累到临界浓度 ,AHLs与胞内特异受体结合 ,启动致病因子的表达。利用AHLs降解酶和AHLs类似物的特性 ,干扰和破坏病原菌的AHLs 群体感应机制 ,将为利用现代生物技术防治此类细菌病害开辟了一条全新的途径

关 键 词:细菌群体感应机制  N-酰基高丝氨酸内酯  细菌信息素  生物防治
文章编号:1001-9383(2003)02-0124-05
修稿时间:2003年2月18日

Bacterial quorum sensing and pathogenicity of plant and animal bacterial pathogens
SONG Shui shan ,ZHAO Zhan liang ,WANG Li jie ,BAI Zhi qi.Bacterial quorum sensing and pathogenicity of plant and animal bacterial pathogens[J].Journal of The Hebei Academy of Sciences,2003,20(2):124-128.
Authors:SONG Shui shan  ZHAO Zhan liang  WANG Li jie  BAI Zhi qi
Institution:SONG Shui shan 1,ZHAO Zhan liang 2,WANG Li jie 2,BAI Zhi qi 2
Abstract:Bacterial N Acyl L homoserine lactones (AHLs) mediated quorum sensing is involved in the regulation of diverse biological functions. As the bacterial pathogen population density increases, AHLs concentration secreted by pathogen reaches a threshold and then interacts with their intracellular receptors and triggers expression of virulence genes. It is a promising approach to biologically control bacterial diseases in plant and animal by manipulating bacterial AHL quorum sensing with AHLs degrading enzyme and AHL homology.
Keywords:Bacterial quorum sensing  N acyl  L homoserine lactones  Bacterial signal  Bio control  
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