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GABA-mimetic action of etomidate
Authors:R. H. Evans  R. G. Hill
Affiliation:(1) Department of Pharmacology, Medical School, University of Bristol, BS8 1TD Bristol, (England)
Abstract:
Summary A comparison of antagonism by bicuculline or strychnine of the effects of GABA or etomidate on rat isolated superior cervical ganglia, frog isolated hemisected spinal cords and rat central neurones in vivo indicates that etomidate has GABA-mimetic actions.Acknowledgments. This work was supported by the Medical Research Council and etomidate was provided by Janssen Pharmaceutica.
Keywords:
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