| 萘酰亚胺类DNA嵌入剂的合成与抗肿瘤活性的研究 |
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| 引用本文： | 李建,林翠花,潘晓茹,梁足培.萘酰亚胺类DNA嵌入剂的合成与抗肿瘤活性的研究[J].潍坊学院学报,2009,9(6):89-92. |
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| 作者姓名： | 李建 林翠花 潘晓茹 梁足培 |
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| 作者单位： | 潍坊学院,山东,潍坊,261061 |
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| 摘 要： | 综述了萘酰亚胺类DNA嵌入剂抗肿瘤药物的合成、结构与活性的关系及其与DNA的作用机制,展望了DNA嵌入剂抗肿瘤药物的发展前景。
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| 关 键 词： | 萘酰亚胺 DNA嵌入剂 抗肿瘤活性 |
Studies on Synthesis and Antitumor Activity of Naphthalimides as DNA Intecalators |
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| LI Jian,LIN Cui-hua,PAN Xiao-ru,LIANG Zu-pei.Studies on Synthesis and Antitumor Activity of Naphthalimides as DNA Intecalators[J].Journal of Weifang University,2009,9(6):89-92. |
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| Authors: | LI Jian LIN Cui-hua PAN Xiao-ru LIANG Zu-pei |
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| Institution: | (Weifang University,Weifang 261061,China) |
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| Abstract: | This paper reviewed synthesis,relationship between structure and antitumor activity of naphthalimides and mechanisms of DNA intecalators.Development of naphthalimide DNA intecalators as antitumor drugs was prospected. |
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| Keywords: | naphthalimides DNA intecalators antitumor activity |
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