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Inhibition of noradrenaline release from sympathetic nerves by pentobarbital
Authors:M Göthert  J -M Rieckesmann
Institution:(1) Pharmakologisches Institut der Universität Hamburg, Martinistr. 52, D-2000 Hamburg 20, (Federal Republic of Germany)
Abstract:Summary Pentobarbital concentrations of 10–100 mgrM selectively inhibited the noradrenaline release evoked by activation of the nicotinic receptors on the terminals sympathetic nerves of the rabbit heart. Higher concentrations also decreased the noradrenaline release induced by KCl or by electrical stimulation of the nerve axons.This paper is dedicated to Professor Dr. G. Malorny on the occasion of his 65th birthday.Acknowledgment: We thank Mrs G. Thielecke for technical assistance.
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