| 环酯红霉素片溶出度测定方法研究 |
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| 引用本文： | 聂忠莉,刘昌平,王晓玲,刘静.环酯红霉素片溶出度测定方法研究[J].成都大学学报(自然科学版),2013,32(2):116-120. |
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| 作者姓名： | 聂忠莉 刘昌平 王晓玲 刘静 |
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| 作者单位： | 成都大学生物产业学院,四川成都,610106;成都欣捷高新技术开发有限公司,四川成都,610041 |
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| 摘 要： | 以磷酸盐缓冲液（pH6．8）为溶出介质，利用紫外分光光度法测定，建立环酯红霉素片溶出度的测定方法．实验结果表明，环酯红霉素在24．08—48．16μg·mL-1的浓度范围内线性关系良好，该方法可用于完善环酯红霉素片的质量标准．
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| 关 键 词： | 环酯红霉素片 溶出度 紫外分光光度法 |
Study on Determination Method for Dissolution of Erythromycin Cyclic 11,12-Carbonate Tablets |
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| NIE Zhongli
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LIU Changping
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WANG Xiaoling
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LIU Jing.Study on Determination Method for Dissolution of Erythromycin Cyclic 11,12-Carbonate Tablets[J].Journal of Chengdu University (Natural Science),2013,32(2):116-120. |
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| Authors: | NIE Zhongli LIU Changping WANG Xiaoling LIU Jing |
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| Institution: | 1.School of Biological Industry,Chengdu University,Chengdu 610106,China;2.Chengdu Xinjie Hi-tech Development Co.,Ltd.,Chengdu 610041,China) |
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| Abstract: | Taking phosphate buffer（pH6.8） as dissolution medium and using UV-spectmphotometric meth- od for determination, we establish the determination method for dissolution of erythromycin cyclic 11,12- carbonate tablets. The experimental result shows that the linear feature of erythmmycin cyclic 11,12-car- bonate is good within the density range 24.08-48.16/ag-mL-1 ,and this method can be used to improve the quality standard of erythromycin cyclic 11,12-carbonate tablets. |
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| Keywords: | erythromycin cyclic 11 12-carbonate tablets dissolution UV-spectrophotometric method |
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