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三种幽门螺杆菌检测方法的评价
引用本文:万远太,孙姣娥.三种幽门螺杆菌检测方法的评价[J].武汉科技大学学报(自然科学版),2000,23(1):101-102.
作者姓名:万远太  孙姣娥
作者单位:武汉科技大学医学院,武汉,430080
摘    要:采用细菌培养、尿素酶试验和酶免疫技术同时进行Hp检测,对三种检测方法进行评估。以细菌培养为金标准,尿素酶试验的灵敏性和特异性分别为96.51%和96%,EIA法为95.35%和86%。细菌培养对Hp感染具有确认价值,但耗时较长,检测过程较复杂。尿毒酶试验简便快捷,适宜于在胃镜室快速检测以及在基层医院普及开展。EIA灵敏性高,特异性稍低,但仍不失为一种Hp感染血清流行病学调查的有效手段。

关 键 词:幽门螺杆菌  酶免疫  检测方法  评价  上消化道疾病
修稿时间:1999-12-13

Evaluation of Clinical Significances of Three Test Methods to Detect Helicobacter Pylori
WAN Yuan-tai,SUN Jiao-e.Evaluation of Clinical Significances of Three Test Methods to Detect Helicobacter Pylori[J].Journal of Wuhan University of Science and Technology(Natural Science Edition),2000,23(1):101-102.
Authors:WAN Yuan-tai  SUN Jiao-e
Abstract:Helicobacter pylori(Hp)was tested with culture,urease test and EIA.The clinical values of these methods were evaluated in this paper.As a golden criterion with culture,urease test had a sensitivity of 96.51% and a specificity of 96% and EIA had a sensitivity of 95.35% and a specificity of 86%.It was obvious that microbiological test had diagnostic significance for Hp infection,but the period of observation was too long and its operation was very complex.Urease test was a convenient and rapid method so it was suitable for direct detection in endoscopy room or in poorly equipped hospital in the countryside.Although EIA had high sensitivity and low specificity,yet it was a reliable method for the seraepidemiologic investigation of Hp infection.
Keywords:Hp  culture  urease test  EIA
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