| 利用硼与对甲氨基苯甲酸褪色光度法测定药物和生物样品中的硼 |
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| 引用本文： | 高成庄,刘玉荣,李全民,张甜甜.利用硼与对甲氨基苯甲酸褪色光度法测定药物和生物样品中的硼[J].河南师范大学学报(自然科学版),2008,36(4). |
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| 作者姓名： | 高成庄 刘玉荣 李全民 张甜甜 |
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| 作者单位： | 1. 河南师范大学,化学与环境科学学院,河南,新乡,453007;焦作师范高等专科学校,化学系,河南,焦作,454000
2. 河南师范大学,化学与环境科学学院,河南,新乡,453007 |
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| 基金项目： | 河南省教育厅自然科学基金 |
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| 摘 要： | 建立了利用对甲氨基苯甲酸测定硼的新方法.研究表明,对甲氨基苯甲酸与硼在pH=10.00发生褪色反应,褪色最大波长λmax=242 nm,硼的浓度在0.22~21.6μg.mL-1范围内与吸光度(A)降低程度呈良好线性关系,线性回归方程为A=-0.035-0.016 C,相关系数r=0.999,检测限为0.18μg.mL-1,回收率为98.7%~101%,该方法能够直接用于药物和生物样品中硼的测定,结果满意.
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| 关 键 词： | 硼 对甲氨基苯甲酸 褪色光度法 |
A Novel Method of the Determination of Boron with AminomethylbenzoicAcid by Discoloring Spectrophotometry in Pharmaceutical and Biological Samples |
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| GAO Cheng-zhuang,LIU Yu-rong,LI Quan-min,ZHANG Tian-tian.A Novel Method of the Determination of Boron with AminomethylbenzoicAcid by Discoloring Spectrophotometry in Pharmaceutical and Biological Samples[J].Journal of Henan Normal University(Natural Science),2008,36(4). |
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| Authors: | GAO Cheng-zhuang LIU Yu-rong LI Quan-min ZHANG Tian-tian |
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| Abstract: | A novel method is described for the determination of boron(B) with Aminomethylbenzoic Acid(PAMBA) by discoloring spectrophotometry in this paper.The study indicates that at pH 10.00 the absorbance of PAMBA in aqueous solution decreases when boric acid(BA) is added to the solution.Beer′s law is obeyed in the range of boron concentrations of 0.22~21.60 μg·mL-1 at the maximal discoloring wavelength of 242 nm.The equation of linear regression is A=-0.038-0.016 C,with a linearly correlation coefficient of 0.999.The detection limit is 0.18 μg·mL-1,RSD is 0.11%,and recovery is in the range of 98.7%~101%.The method is successfully applied to the determination of boron in pharmaceutical and biological samples. |
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| Keywords: | boron aminomethylbenzoic acid discoloring spectrophotometry |
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