Biosynthesis of roquefortine and 3,12-dihydroroquefortine by the culturePenicillium farinosum |
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| Authors: | A. G. Kozlovsky T. F. Solovieva T. A. Reshetilova G. K. Skryabin |
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| Affiliation: | (1) Institute of Biochemistry and Physiology of Microorganisms, USSR Academy of Sciences, USSR-142292 Pushchino, Moscow region, USSR |
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| Abstract: | ![]()
Summary A new culturePenicillium farinosum synthesizing roquefortine and 3, 12-dihydroroquefortine was found. UnlikeP. roqueforti, a known producer of these compounds, the culture under study does not synthesize clavine alkaloids. The maximal roquefortine content was observed in the late logarithmic and early stationary growth phases while the maximal 3, 12-dihydroroquefortine content was obtained in the beginning of the stationary phase.Thanks are due to Drs V. M. Adanin and M. Yu. Nefedova for mass- and IR-spectra. |
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