|
|||||
|
|
An assessment of the effect of hormone and neurotransmitters on adenine and gluanine derivatives simultaneously in rat brain cortical slices |
|
| Authors: | I Das J S de Belleroche |
| Institution: | (1) Department of Experimental Pathology, Section of Biochemistry, Cardiothoracic Institute, Brompton, SW3 London;(2) Department of Biochemistry, Imperial College of Science and Technology, SW7 London, (England);(3) Present address: Medical Research Council Toxicology Unit, Clinical Section, St. Bartholomew's Hospital Medical College, Charterhouse Square, EC1M 6BQ London |
| Abstract: | Summary A 2-dimensional thin-layer method has been developed for the separation on cellulose of adenine and guanine derivatives. Using incubated rat cerebral cortex slices it was shown that noradrenaline and acetylcholine stirnulated cAMP and cGMP production respectively but glutamate and  -aminobutyric acid stimulated production of both cyclic nucleotides. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |