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人参皂苷粉、银杏叶提取物对鸡胚绒毛尿囊膜血管新生的作用
引用本文:崔杰,何正有,李维,刘婧,聂敏奎. 人参皂苷粉、银杏叶提取物对鸡胚绒毛尿囊膜血管新生的作用[J]. 成都大学学报(自然科学版), 2016, 35(4): 324-327. DOI: 10.3969/j.issn.1004-5422.2016.04.003
作者姓名:崔杰  何正有  李维  刘婧  聂敏奎
作者单位:成都大学四川抗菌素工业研究所,四川成都,610052;成都大学四川抗菌素工业研究所,四川成都,610052;成都大学四川抗菌素工业研究所,四川成都,610052;成都大学四川抗菌素工业研究所,四川成都,610052;成都大学四川抗菌素工业研究所,四川成都,610052
摘    要:
为探讨人参皂苷粉和银杏叶提取物对鸡胚绒毛尿囊膜血管新生的影响,取孵育9天的种蛋,通过暴露鸡胚绒毛尿囊膜来建立模型,28只存活的鸡胚随机分为4组,包含两组空白载体的对照,一组加人参皂苷粉水溶液,一组加含银杏叶提取物药膜,作用3天后,观察分析鸡胚绒毛尿囊膜上血管生长的变化.结果显示:人参皂苷粉组,血管数量明显增多,但血管直径变细,颜色变淡;银杏叶提取物组,血管数量显著增多,血管颜色加深.研究发现:人参皂苷粉既能促进血管生成,又能抑制血管生成,总体表现为抑制;银杏叶提取物能够明显的促进血管的新生.

关 键 词:鸡胚绒毛尿囊膜  人参皂苷粉  银杏叶提取物

Angiogenesis Effects of Ginsenoside Powder and Ginkgo Biloba Extract on Chick Embryo Chorioallantoic Membrane Model
CUI Jie,HE Zhengyou,LI Wei,LIU Jing,NIE Minkui. Angiogenesis Effects of Ginsenoside Powder and Ginkgo Biloba Extract on Chick Embryo Chorioallantoic Membrane Model[J]. Journal of Chengdu University (Natural Science), 2016, 35(4): 324-327. DOI: 10.3969/j.issn.1004-5422.2016.04.003
Authors:CUI Jie  HE Zhengyou  LI Wei  LIU Jing  NIE Minkui
Abstract:
The paper investigates the angiogenesis effects of Ginsenoside powder and Ginkgo Biloba Extract on the chick embryo choriallantoic membrane (CAM ) model .Fertilized chicken eggs are incubated and the CAM membrane is exposed to build a module on the 9th day .Twenty-eight surviving chick embryos are ran-domly divided into 4 groups:two groups with blank carrier compare ,one group with Ginsenoside powder’s solution ,and one group with Ginkgo Biloba Extract’s sensitive layer .After 3 days ,we observe and analyze the changes of vascular growth on the CAM embrane .The results show that as for the group with Ginsen-oside powder ,the number of blood vessels increases significantly ,but the diameter of blood vessels becomes thinner and the color becomes lighter .For the group with Ginkgo Biloba extract ,the number of blood vessels increases significantly and the color deepens .The conclusion drawn from the paper is that Ginsenoside pow-der can not only promote angiogenesis ,but also inhibit angiogenesis and its overall performance is sup-pressed .Ginkgo Biloba extract can significantly promote angiogenesis .
Keywords:chick embryo chorioallantoic membrane  Ginsenoside powder  Ginkgo Biloba extract
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