特大型剖分调心滚子轴承加工的研究

本文提出了特大型剖分调心滚子轴承原加工工艺流程的不足,并对其进行了调整和改进,分析了加工过程中的难点,并提出了解决方案。     

基于FFT的互感式电流信号检测装置的设计

为解决对电路中电流信号的实时监测及谐波分析问题,利用传感器技术设计出一套高精度基于FFT( Fast Fourier Transform) 的互感式电流信号检测装置。该装置可对环路电流信号进行非接触式测量,硬件电路包括互感式电流传感器和检波电路,软件部分以STM32 为主控制器,对信号进行傅立叶变换得到频率和幅度信息。这种以微处理器为核心的测量装置可以实现测量自动化和功能多样化,在工业领域具有一定的应用价值。经实验检测,该系统的频率分辨率可达到1 Hz,幅度分辨率可达到0． 5 mA,测量电流信号频率误差小于2% ,幅度误差小于5%。     

MiR-205 inhibits the invasion and migration of esophageal squamous cell carcinoma by modulating SMAD1 expression

Esophageal squamous cell carcinoma （ESCC） is one of the most lethal cancers worldwide. In this study, we aimed to investigate the underlying mechanisms of metastasis inhibition by miR-205 in ESCC. In microRNA （miRNA） array and quantitative RT-PCR analyses, we found that the expression level of miR-205 was significantly lower in patients with lymph node metastasis compared with that in patients without lymph node metastasis. After transfection of miR-205 mimics or inhibitors into ESCC cell lines, a significant negative correlation was observed between the expression level of miR-205 and Smad 1. In luciferase reporter assays, we revealed that miR- 205 inhibited the expression of SMAD1 by targeting the 3＇ untranslated region （3＇-UTR） of SMAD1 mRNA in ESCC cells. Furthermore, our results showed that miR-205 sup- pressed the invasion and migration of ESCC cells, whereas Smadl increased their invasion and migration. Taken together, our study demonstrates that miR-205 functions as a suppressor of tumor metastasis by regulating SMAD1 expression through targeting the 3＇-UTR of SMAD1 mRNAin ESCC. Therefore, miR-205 may be a potential therapeutic target for miRNA-based therapy of ESCC.     

快速加权核范数最小化的SAR图像去噪算法

提出快速加权核范数最小化(fast weighted nuclear norm minimization,FWNNM)的合成孔径雷达(synthetic aperture radar,SAR)图像去噪算法。首先采用对数变换将SAR图像的乘性噪声变换为加性噪声,然后利用非局部相似性对变换后的图像进行块匹配,随后根据低秩模型框架,用随机奇异值分解替换加权核范数最小化(weighted nuclear norm minimization,WNNM)算法中的奇异值分解进行低秩矩阵逼近,再采用梯度直方图保存的方法对图像进行纹理增强,最终实现了对SAR图像快速去噪。在MSTAR数据库上的实验结果表明,与已有方法相比,所提方法在SAR图像去噪和边缘保持方面是有效的,并且比WNNM去噪速度快3倍。     

加氢空冷器注水管道孔板流场及压降特性分析

加氢反应流出物空冷器(reactor effluent air cooler,简称REAC)作为石化装置重要冷换设备铵盐腐蚀风险较大,工程上通常采用空冷器前注水消除NH4 Cl等铵盐沉积堵管问题,因此,注水效果好坏直接影响石化装置的安全稳定运行.以某石化企业REAC前注水孔板为研究对象,通过分析不同孔数、等效直径比、相对厚度等因素对孔板压损系数的影响机理,评估孔板结构对多元流体均流平衡效果优劣.研究结果表明:在相同的孔数和等效直径比下,压损系数随孔板相对厚度的增加先快速减小随后趋于稳定,其临界孔板相对厚度为0. 822.在相同等效直径比和相对厚度下,薄孔板的压损系数随孔数增加先减小后增大,压损系数与管道出口流量呈负相关关系.综合考量下孔板相对厚度为1.474时,单孔孔板结构均流平衡效果最好.     

仓库智能防控软件系统总体设计

针对复杂环境下仓库智能防控系统中央控制、联调联试的需求,研究了软件系统总体框架设计问题.利用数据流和面向对象的方法,分析了软件系统功能需求,对系统的功能结构和网络构成进行了设计,并提出了相应的软件优化建议.     

Melatonin and mitochondrial function during ischemia/reperfusion injury

Ischemia/reperfusion (IR) injury occurs in many organs and tissues, and contributes to morbidity and mortality worldwide. Melatonin, an endogenously produced indolamine, provides a strong defense against IR injury. Mitochondrion, an organelle for ATP production and a decider for cell fate, has been validated to be a crucial target for melatonin to exert its protection against IR injury. In this review, we first clarify the mechanisms underlying mitochondrial dysfunction during IR and melatonin’s protection of mitochondria under this condition. Thereafter, special focus is placed on the protective actions of melatonin against IR injury in brain, heart, liver, and others. Finally, we explore several potential future directions of research in this area. Collectively, the information compiled here will serve as a comprehensive reference for the actions of melatonin in IR injury identified to date and will hopefully aid in the design of future research and increase the potential of melatonin as a therapeutic agent.     

智能天线与多用户检测的联合抗干扰模型构建

联合抗多址干扰技术是目前移动通信技术研究的热点.将智能天线与多用户检测技术相结合可抑制相干干扰,改善系统的误码率性能,提高移动通信系统的有效性与可靠性,优化无线资源的利用率.提出了采用智能天线接收后进行多用户检测的CDMA系统模型,并引入基于LMS算法的自适应滤波器来消除窄带干扰.Matlab软件仿真结果表明,联合抗干扰模型较好地提升了误码率性能.     

短距离加密无线数据传输系统的设计与实现

针对传统无线数传系统不能加密以保证数据和文件的安全性问题,设计一种利用Noekeon算法加密文件的短距离无线数传系统.该系统由软件和硬件共同运行:利用C#语言实现主控界面的编程,将Noekeon算法密钥存放在USBkey里,在系统界面调用Noekeon算法对文件进行加解密,操作USB1101-232无线数传模块对文件进行传输,利用MD5算法验证收发双方的HASH值.测试结果表明,该系统可保证文件传输的可靠性和安全性.