Glycolipid transfer protein and intracellular traffic of glucosylceramide

Glycolipid transfer protein (GL-TP), a nonglycosylated protein with a molecular weight of 22,000 K, has been purified from pig brain. The protein transfers, by a carrier mechanism, glycolipids with a beta-glucosyl or beta-galactosyl residue directly linked to either ceramide or diacylglycerol. GL-TP appears to be present in most animal cells, and evidence has been obtained which indicates that it is a cytoplasmic protein. Little is known about the function of GL-TP. Current evidence indicates that glycosphingolipid glycosylation occurs at the luminal side of the Golgi apparatus, except for the glucosylation of ceramide, which has been shown to occur at the cytoplasmic side of the Golgi or endoplasmic membrane. It appears most likely that GL-TP participates in the intracellular traffic of glucosylceramide.     

Purealidin A,a new cytotoxic bromotyrosine-derived alkaloid from the Okinawan marine spongePsammaplysilla purea

Summary A new bromotyrosine-derived alkaloid with antileukemic activity, purealidin A (5), has been isolated from the Okinawan marine spongePsammaplysilla purea and its chemical structure elucidated on the basis of the spectroscopic data.     

Effect of hormones on acid mucopolysaccharide synthesis in mouse skin. An enzyme study

Zusammenfassung Die Aktivität dreier mucopolysac-charidsynthetisierender Enzyme in der Haut normaler Mäuse wurde von Cortison und DOCA gehemmt, von Östradiol und Testosteron hingegen stimuliert. Eine Ausnahme bildet die Gruppe testosteronbehandelter weiblicher Mäuse.     

逐步熔融凝固加工

介绍逐步熔融加工的原理，即向非诱导性的成形模内连续提供诱导性的颗粒或粉末状的原材料，利用高频加热使模内的材料熔化并保持一个较窄的区域，通过成形模与加热源的相对移动，使材料自下而上逐步地熔融和凝固，达到一次成形的目的，此外还介绍了它适应范围宽及制品的优良的物理和力学性能等优点。     

Oriential orchid (Cymbidium pumilum) attracts drones of the Japanese honeybee (Apis cerana japonica) as pollinators

The discovery that drones of the Japanese honeybee (Apis cerana japonica) pollinate the oriental orchid (Cymbidium pumilum) is reported. Drones are attracted to the orchid flower aroma mainly during their mating flights in April through May. Some drones cluster on the flower racemes and others insert their heads deep into the flowers. Drones with pollinia on their scutellum visit other orchids, which facilitates pollination. Individual workers and swarming colonies are also strongly attracted by the flower aroma, but the allopatric western honeybee (Apis mellifera) is not attracted.     

Stimulation of human chorionic gonadotropin and progesterone secretion by tumor promoters,phorbol ester and teleocidin B,in cultured choriocarcinoma cells

Summary Both 12-O-tetradecanoyl-phorbol-1-acetate and teleocidin B stimulated the secretion of human chorionic gonadotropin by cultured choriocarcinoma cells. These tumor promoters also stimulated production of progesterone in the cells. However, the 2 tumor promoters did not exert a marked effect on the cellular binding of epidermal growth factor that also had a stimulatory effect on production of these hormones.