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A. Marquet V. Larraga J. L. Diez C. Amela J. Rodrigo E. Muñoz A. Pestaña 《Cellular and molecular life sciences : CMLS》1984,40(9):977-980
Summary Fatty acid anilides, the major xenobiotic found in the cooking oils responsible for the Spanish toxic oil syndrome, are immunogenic for rabbits as ascertained by a skin test reaction, the characterization of specific antibodies against anilides and the immunofluorescent detection of anilide dependent antigens in tissue slices from treated animals.Acknowledgments. This work was supported by a grant from the Fondo de Investigaciones Sanitarias to the C.S.I.C. Programme on Toxic Oil Syndrome. We are indebted to Dr M. Studt and Dr E. Fernández-Alvarez, from the National Center for Organic Chemistry, C.S.I.C., for kindly providing the synthetic fatty acid anilides. We also wish to thank Prof. C. Gitler for helpful discussion. 相似文献
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Immunogenicity of fatty acid anilides in rabbits and the pathogenesis of the Spanish toxic oil syndrome 总被引:1,自引:0,他引:1
Fatty acid anilides, the major xenobiotic found in the cooking oils responsible for the Spanish toxic oil syndrome, are immunogenic for rabbits as ascertained by a skin test reaction, the characterization of specific antibodies against anilides and the immunofluorescent detection of 'anilide dependent antigens' in tissue slices from treated animals. 相似文献
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