含丝氨酸残基手性肽核酸单体的合成

对文献合成方法进行了改进．以N—Boc氨基酸与自制甲烷磺酸酯反应，制备N—Boc氨基酸丙烯酯，以混合酸酐法实现关键中间体与1-胸腺嘧啶乙酸的缩合，总收率为26．4％，比文献方法提高了12％，成本降低，制备了含丝氨酸残基碱基为胸腺嘧啶的手性肽核酸单体．     

合成肽核酸单体组氨酸的保护策略

以L-组氨酸为起始原料,设计合成了含组氨酸残基的手性肽核酸单体.以叔丁氧羰基(Boc)保护α-氨基,羧基形成苄酯加以保护,分别以苄氧羰基(Cbz)及2,4-二硝基苯基(Dnp)作为咪唑基的临时和永久保护基,共九步反应,手性肽核酸单体总收率13.3%.     

Studies of Several Systems with Air Electrode Electro-Synthesizing H_2O_2 on the Spot for Degr ading Aniline in Aqueous

0　ＩｎｔｒｏｄｕｃｔｉｏｎＴｈｅｍｅｔｈｏｄｏｆｍｉｎｅｒａｌｉｚｉｎｇｏｒｇａｎｉｃｔｏｘｉｃａｎｔｓｉｎｔｈｅｗａｓｔｅｗａｔｅｒｂｙｇｅｎｅｒａｔｉｎｇ·ＯＨｒａｄｉｃａｌｓｈａｓｂｅｃｏｍｅｆｏｃｕｓｏｆｃｈｅｍｉｃａｌｔｈｅｏｒｉｅｓａｎｄｔｅｃｈｎｉｃａｌｒｅｓｅａｒｃｈｅｓｉｎｔｈｅｅｎｖｉｒｏｎｍｅｎｔｐｒｏｔｅｃｔｉｏｎ[1] .Ｂｅｃａｕｓｅ·ＯＨｒａｄｉｃａｌｉｓａｓｔｒｏｎｇｏｘｉｄｉｚｅｒｗｉｔｈｓｔａｎｄａｒｄｐｏｔｅｎｔｉａｌｏｆ2 .80Ｖ ,ｗｉｔｈｉｔ,ｔｈｅｓｔａｂｌｅ…     

(S)-2-甲氧基环己酮的合成

（S）-2-甲氧基环己酮为制备抗菌药Tribactam侧链的关键中间体．本研究工作设计以1，2-环氧环己烷为起始原料，经甲醇取代开环、酯化、缬氨酸手性拆分、皂化、氧化，得到光学纯的（S）-2-甲氧基环己酮；总收率14．32％．     

The characteristic of electrochemical oxidation of aniline on SnO2/Ti electrode

The characteristic of electrochemical oxidation of aniline on SnO₂/Ti electrode is studied. The results indicate that SnO₂/Ti electrode dopedF plays a wonderful role in the oxidation of aniline comparing with Pt electrode. The kinetics factors that influence the oxidation rate of aniline on the SnO₂/Ti electrode are determined by the dissolving of the film on the electrode. The dissolving of the film consisted of intermediate products on the electrode is the slow step. The effects of aniline concentration, pH in aniline solution and the current density (i) on the rate of aniline oxidation, the complexity of intermediate products and the basic category of the intermediate products consisted of the film are introduced. Foundation item: Supported by the National Natural Science Foundation of PRC(10971023) Biography: Wany Yu-ling (1975-), female, Master, research direction: photochemical catalysis and electochemical catalysis.     

An effective novel reaction system for the photo-degradation of aqueous organic pollutants

A novel reaction system consisted of a supported TiO₂ film electrode, a Ru−Ti oxide film electrode and air (oxygen) electrode is reported. The air (oxygen) electrode can provide H₂O₂ continuously for homogeneous photochemical oxidation reaction on the spot. In this reactor, degradation reaction of aniline occur from interface of TiO₂ film to all solution which is irradiated by ultraviolet ray. The degradation rate of aniline was characterized by measuring the change of chemical oxygen demand (COD) in solution under different conditions. It was found that the degradation rate of aniline in the novel system increased apparently as compared with single heterogeneous photocatalysis and homogeneous photochemistry system. It can be explained in terms of combining acts of heterogeneous photocatalysis and homogeneous photochemistry. Foundation item: Supported by the National Natural Science Foundation of China (10791033) Biography: CAI Nai-cai (1946-), male, Associate professor, Research direction: electrochemical catalysis and photocatalysis.     

FPS-1306的合成研究

以1,2,4-三-O-乙酰基-4-O-苄基-α/β-L艾杜糖醛酸甲酯为起始原料,经溴化、糖苷化、脱乙酰基和选择性乙酰化合成了甲基6-O-乙酰基-3-O-苄基-2-苄氧碳酰氨基-2-脱氧-4-O-(2-O-乙酰基-3-O-苄基-α-L-吡喃艾杜糖醛酸甲酯)-α-D-吡喃葡萄糖(FPS-1306),其中2个中间体为新化合物,结构经1H NMR、13C NMR和MS表征.     

Studies of several systems with air electrode electro-synthesizing H<Subscript>2</Subscript>O<Subscript>2</Subscript> on the spot for degrading aniline in aqueous

A gas diffusion electrode (air electrode) with a high current efficiency of electro-synthesizing H₂O₂ using O₂ in air was prepared. The several systems with air electrode as cathode of electro-synthesizing H₂O₂ on the reaction spot for degrading aniline in aqueous—electro-Fenton system, photo-excitation electro-H₂O₂ system and photo-electro-Fenton system, were developed. The rates of decomposition of H₂O₂ and mineralization of aniline were experimentally measured respectively under different conditions, and the results indicated there has an excellent parallel relation between decomposition rate of H₂O₂ and mineralization rate of aniline. Especially, photo-electro-Fenton system, where H₂O₂ is decomposed the fastest, is the best system of oxidizing and degrading organic toxicants. Compared photo-electro-Fenton system with photo-Fenton system, important role is revealed in the interface of air electrode. In this paper, the mineralization mechanism of aniline in the photo-electro-Fenton system was also discussed. Foundation item: Supported by the National Natural Science Foundation of China (200710026) and Foundation of Environmental Sciences Academy of Jiangsu Province. Biography: Cao xiao-yu (1979-), male, Master candidate, research direction: Electrochemistry