全文获取类型
收费全文 | 425篇 |
免费 | 0篇 |
国内免费 | 7篇 |
专业分类
系统科学 | 17篇 |
教育与普及 | 6篇 |
理论与方法论 | 7篇 |
现状及发展 | 75篇 |
研究方法 | 58篇 |
综合类 | 235篇 |
自然研究 | 34篇 |
出版年
2020年 | 4篇 |
2019年 | 2篇 |
2018年 | 3篇 |
2016年 | 3篇 |
2015年 | 4篇 |
2014年 | 14篇 |
2013年 | 13篇 |
2012年 | 23篇 |
2011年 | 66篇 |
2010年 | 15篇 |
2009年 | 6篇 |
2008年 | 36篇 |
2007年 | 23篇 |
2006年 | 31篇 |
2005年 | 23篇 |
2004年 | 36篇 |
2003年 | 23篇 |
2002年 | 31篇 |
2001年 | 2篇 |
2000年 | 1篇 |
1999年 | 3篇 |
1997年 | 3篇 |
1996年 | 1篇 |
1994年 | 2篇 |
1993年 | 2篇 |
1992年 | 6篇 |
1991年 | 1篇 |
1989年 | 4篇 |
1988年 | 2篇 |
1987年 | 1篇 |
1986年 | 6篇 |
1985年 | 3篇 |
1984年 | 4篇 |
1983年 | 3篇 |
1982年 | 2篇 |
1981年 | 1篇 |
1980年 | 2篇 |
1978年 | 1篇 |
1976年 | 2篇 |
1975年 | 3篇 |
1973年 | 2篇 |
1972年 | 2篇 |
1971年 | 2篇 |
1970年 | 7篇 |
1969年 | 1篇 |
1968年 | 1篇 |
1966年 | 2篇 |
1965年 | 1篇 |
1960年 | 1篇 |
1958年 | 1篇 |
排序方式: 共有432条查询结果,搜索用时 265 毫秒
1.
2.
分析了抗生素类药物盐酸环丙沙星对水中不同食物链水生生物包括小球藻、发光菌、大型蚤、孔雀鱼的影响,其急性毒性EC50或者LC50数值分别为20.61,63.27,135.15,365.00 mg·L-1。毒性作用规律结果显示,随着生物链等级的升高,生物对环丙沙星的耐受程度升高。将综合评价因子(PEC/PNEC)作为环境风险表征参数,对大连开发区污水处理厂排水及大连湾沿海养殖区中存在的盐酸环丙沙星进行风险分析,发现盐酸环丙沙星在沿海养殖区水域中的环境风险高于污水处理厂排水。小球藻的综合评价因子数值范围最大,可作为评价水体中盐酸环丙沙星残留风险等级的生物标志物。 相似文献
3.
4.
记述中国〖XC5XCC.TIF〗目2新种, 井冈山无齿股〖XC5XCC.TIF〗Parasipyloideajinggangshanensis Ho, sp nov.及七州瘦〖XC5XCC.TIF〗Macellina qizhouense Ho, sp nov。新种模式标本存放于广州中山大学生物博物馆。 相似文献
5.
Ong CK Subimerb C Pairojkul C Wongkham S Cutcutache I Yu W McPherson JR Allen GE Ng CC Wong BH Myint SS Rajasegaran V Heng HL Gan A Zang ZJ Wu Y Wu J Lee MH Huang D Ong P Chan-on W Cao Y Qian CN Lim KH Ooi A Dykema K Furge K Kukongviriyapan V Sripa B Wongkham C Yongvanit P Futreal PA Bhudhisawasdi V Rozen S Tan P Teh BT 《Nature genetics》2012,44(6):690-693
Opisthorchis viverrini-related cholangiocarcinoma (CCA), a fatal bile duct cancer, is a major public health concern in areas endemic for this parasite. We report here whole-exome sequencing of eight O. viverrini-related tumors and matched normal tissue. We identified and validated 206 somatic mutations in 187 genes using Sanger sequencing and selected 15 genes for mutation prevalence screening in an additional 46 individuals with CCA (cases). In addition to the known cancer-related genes TP53 (mutated in 44.4% of cases), KRAS (16.7%) and SMAD4 (16.7%), we identified somatic mutations in 10 newly implicated genes in 14.8-3.7% of cases. These included inactivating mutations in MLL3 (in 14.8% of cases), ROBO2 (9.3%), RNF43 (9.3%) and PEG3 (5.6%), and activating mutations in the GNAS oncogene (9.3%). These genes have functions that can be broadly grouped into three biological classes: (i) deactivation of histone modifiers, (ii) activation of G protein signaling and (iii) loss of genome stability. This study provides insight into the mutational landscape contributing to O. viverrini-related CCA. 相似文献
6.
Behavior of migrant birds in relation to temperature was studied and compared to that of resident species in the northern Mojave Desert. Migrants reduced foraging intensity above 30 C, but resident species showed no striking decrease in intensity of foraging at temperatures up to 35 C. Migrant species shifted activities to shaded microhabitats at temperatures between 20 and 30 C; the resident Verdin showed a similar shift at 35 C. Most migrants decreased the amount of time spent foraging at temperatures above 30; Verdins showed a similar but stronger response to temperatures about 30 C. Significant reductions in the use of hovering and hawking maneuvers were found among migrants at temperatures above 30 C. Migrants showed similar types of behavioral adjustments to temperatures as did resident desert species, but they responded earlier in the daily temperature cycle. Desert birds appear to correlate their daily activity strongly with temperature, but nondesert species may respond either to temperature or time of day. 相似文献
7.
The nest of the ant Formica propinqua W. M. Wheeler is reported from Washoe Co., Nevada. 相似文献
8.
GAO George Fu 《科学通报(英文版)》2012,57(31):4100-4102
The evolution of mechanisms to fight pathogens in plants and animals is reflected in the complexity of the components of their so-called immune systems. Higher vertebrates have evolved 相似文献
9.
This paper assesses the international efficiency of the European football betting market by examining the forecastability of match outcomes on the basis of the information contained in different sets of online and fixed odds quoted by six major bookmakers. The paper also investigates the profitability of strategies based on: combined betting, simple heuristic rules, regression models and prediction encompassing. The empirical results show that combined betting across different bookmakers can lead to limited but highly profitable arbitrage opportunities. Simple trading rules and betting strategies based on forecast encompassing are found capable of also producing significant positive returns. Despite the deregulation, globalization and increased competition in the betting industry over recent years, the predictabilities and profits reported in this paper are not fully consistent with weak-form market efficiency. Copyright © 2008 John Wiley & Sons, Ltd. 相似文献
10.
Thirteen Speyeria nokomis apacheana (Edwards) (Nymphalidae) populations from the western Great Basin were assayed for isozyme variability using starch-gel electrophoresis. Eight of the 25 presumptive isozyme loci analyzed were found to be polymorphic. Collections made in 1991and 1992 allowed for between-year comparisons of heterozygosity and the estimation of effective population size for five of the sampled populations. Speyeria nokomis apacheana populations exhibit lower mean heterozygosity levels than other nymphalids. This may be attributed to genetic drift in apparently isolated populations with small effective sizes. 相似文献