Dependence of mutual information of big protein sequence

The mutual information function is used to describe the auto-correlation of amino acids in protein. We find two interesting phenomenon: (1) for any given big protein, the mutual information function l(k) is almost a const, where k is the length of gap. (2) for any two sequence similar proteins, the mutual information are nearly the same. As a consequent, we may use mutual information of protein as a character for sequences comparison. Foundation item: Supported by the National Natural Science Foundation of China (30170214) Biography: Shi Feng ( 1966-), male, Ph. D, Associate professor, research direction: bioinformatics.     

Phylogeny constructed by using diversity increment

A new approach based on the concept of the diversity increment is applied to reconstruct a phylogeny. The phylogeny of the Eutherian orders use concatenated H-stranded amino acid sequences, and the result is consistent with the commonly accepted one for the Eutherians. Foundation item: Supported by the National Natural Science Foundation of China ( 30170214) and the Open Foundation of the State Key Laboratory of Software Engineer, Wuhan University, China. Biography: Shi Feng ( 1966- ), male, Ph. D, Associate professor, research direction: bioinformatics.     

HMM in predicting protein secondary structure

We introduced a new method—duration Hidden Markov Model (dHMM) to predicate the secondary structure of Protein. In our study, we divide the basic second structure of protein into three parts: H (α-Helix), E (β-sheet) and O (others, include coil and turn). HMM is a kind of probabilistic model which more thinking of the interaction between adjacent amino acids (these interaction were represented by transmit probability), and we use genetic algorithm to determine the model parameters. After improving on the model and fixed on the parameters of the model, we write a program HMMPS. Our example shows that HMM is a nice method for protein secondary structure prediction. Foundation item: Supported by the National Natural Science Foundation of China (30170214) Biography: Huang Jing (1977-), female, Master candidate, research direction: bioinformatics.     

抽象空间微分方程解的收敛性

本文研究了抽象空间微分方程解的收敛性问题,得到了有关收敛性的两个定理.     

Interleaver design method for turbo codes based on genetic algorithm

This paper describes a new interleaver construction technique for turbo code. The technique searches as much as possible pseudo-random interleaving patterns under a certain condition using genetic algorithms(GAs). The new interleavers have the superiority of the S-random interleavers and this interleaver construction technique can reduce the time taken to generate pseudo-random interleaving patterns under a certain condition. The results obtained indicate that the new interleavers yield an equal to or better performance than the Srandom interleavers. Compared to the S-random interleaver,this design requires a lower level of computational complexity.     

Mixed search algorithm for protein folding

0　IntroductionThedeterminationofthefoldingpathwayfollowedbyaproteinintheconformationalspacefromthedenaturedstatetothenativestructureisstillanunsolvedproblem .Itsdifficultyismainlyduetotheenormousextensionoftheconformationalspaceandtoitsexponentialgrowthwhenthelengthoftheproteinchainincreases.HowaproteinsolvestheLevinthalparadox[1 ] ,i.e.,howitfoldstoitsnativestructurewithoutanexhaustivesearchintheconforma tionalspace,hasbeenlargelydebatedinRef.[2 5 ].Thenatureofthedrivingforcesinducingtheco…     

00Cr12Ni不锈钢焊接热影响区的组织及韧性

采用Gleeble3800热力模拟试验机模拟了00Cr12Ni不锈钢不同热输入下的焊接热循环.研究了热模拟试样的组织及冲击韧性.实验结果表明,焊接粗晶区晶粒大小和马氏体的体积分数均随热输入的增加而增加;细晶区组织以马氏体为主,有少量的铁素体,晶粒非常细小;焊接粗晶区试样的室温冲击功随热输入的增加而降低;不同热输入下,细晶区模拟试样均具有优良的冲击韧性;粗晶区冲击试样均为脆性断裂,而细晶区冲击试样均为韧性断裂;为得到组织细小、韧性优良的焊接热影响区,应尽量采用小的热输入规范.     

电磁磨料射流增压特性参数优化研究

针对前混合磨料射流设备存在连续性差和后混合磨料射流系统磨料混合不均匀等问题,论文基于电磁磨料浆体射流技术,采用数值模拟分析和实验研究相结合的方法对影响电磁磨料浆体射流增压特性因素进行深入研究。依据前人研究结果,采用数值模拟预测磁通密度和电压两参数对导电介质出口速度及其动能影响情况,搭建了试验平台,结合正交试验特点,并进行试验。试验表明：磁通密度对射流增压特性影响最大,电压次之,验证了数值模拟分析结果,且在磁通密度为0.7 T,电压值为72 V,导电介质浓度选为18 %,极板间距为0.025 m情况下,射流增压特性效果最好。