排序方式: 共有6条查询结果,搜索用时 78 毫秒
1
1.
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs 总被引:6,自引:0,他引:6
Okazaki Y Furuno M Kasukawa T Adachi J Bono H Kondo S Nikaido I Osato N Saito R Suzuki H Yamanaka I Kiyosawa H Yagi K Tomaru Y Hasegawa Y Nogami A Schönbach C Gojobori T Baldarelli R Hill DP Bult C Hume DA Quackenbush J Schriml LM Kanapin A Matsuda H Batalov S Beisel KW Blake JA Bradt D Brusic V Chothia C Corbani LE Cousins S Dalla E Dragani TA Fletcher CF Forrest A Frazer KS Gaasterland T Gariboldi M Gissi C Godzik A Gough J Grimmond S Gustincich S Hirokawa N Jackson IJ Jarvis ED Kanai A 《Nature》2002,420(6915):563-573
2.
3.
Bernd Fritzsch Daniel F. Eberl Kirk W. Beisel 《Cellular and molecular life sciences : CMLS》2010,67(18):3089-3099
In mouse ear development, two bHLH genes, Atoh1 and Neurog1, are essential for hair cell and sensory neuron differentiation. Evolution converted the original simple atonal-dependent neurosensory cell formation program of diploblasts into the derived developmental program of vertebrates that generates
two neurosensory cell types, the sensory neuron and the sensory hair cell. This transformation was achieved through gene multiplication
in ancestral triploblasts resulting in the expansion of the atonal
bHLH gene family. Novel genes of the Neurogenin and NeuroD families are upregulated prior to the expression of Atoh1. Recent data suggest that NeuroD and Neurogenin were lost or their function in neuronal specification reduced in flies, thus changing our perception of the evolution of
these genes. This sequence of expression changes was accompanied by modification of the E-box binding sites of these genes
to regulate different downstream genes and to form inhibitory loops among each other, thus fine-tuning expression transitions. 相似文献
4.
Circadian periodicity of bloof amino-acids in adult men 总被引:4,自引:0,他引:4
5.
6.
1