排序方式: 共有4条查询结果,搜索用时 78 毫秒
1
1.
Bahar R Hartmann CH Rodriguez KA Denny AD Busuttil RA Dollé ME Calder RB Chisholm GB Pollock BH Klein CA Vijg J 《Nature》2006,441(7096):1011-1014
2.
An RNA map predicting Nova-dependent splicing regulation 总被引:1,自引:0,他引:1
Ule J Stefani G Mele A Ruggiu M Wang X Taneri B Gaasterland T Blencowe BJ Darnell RB 《Nature》2006,444(7119):580-586
3.
Hakan Canbaz Musa Dirlik Tahsin Colak Koray Ocal Tamer Akca Oner Bilgin Bahar Tasdelen Suha Aydin 《浙江大学学报(自然科学英文版)》2008,9(6):482-488
Objective: To investigate the effect of recurrent laryngeal nerve (RLN) identification on the complications after total thyroidectomy and lobectomy. Methods: Total 134 consecutive patients undergoing total thyroidectomy or thyroid lobectomy from January 2003 to November 2004 were investigated retrospectively. Patients were divided into two groups: RLN identified (Group A) or not (Group B). The two groups were compared for RLN injury and hypocalcaemia. Results: The numbers of patients and nerves at risk were 71 and 129 in Group A, and 63 and 121 in Group B, respectively, RLN injury in Group A (0) was significantly lower than that in Group B (5 [7.9%]) patients, 7 [5.8%] nerves) for the numbers of patients (P=0.016) and nerves at risk (P=0.006). Temporary hypocalcaemia was significantly higher in Group A than in Group B (14 [24.1%] vs 6 [ 10.3%], P=0.049), Permanent complications in Group B were significantly higher than those in Group A (13 [20.6%] vs 4 [5.6%], P=0.009). Conclusion: RLN injury was prevented and permanent complications were decreased by identifying the whole course and branches of the recurrent laryngeal nerve during total thyroidectomy, 相似文献
4.
Engen JR Wales TE Hochrein JM Meyn MA Banu Ozkan S Bahar I Smithgall TE 《Cellular and molecular life sciences : CMLS》2008,65(19):3058-3073
Src-family kinases are modular signaling proteins involved in a diverse array of cellular processes. All members of the Src
family share the same domain organization, with modular SH3, SH2 and kinase domains followed by a C-terminal negative regulatory
tail. X-ray crystallographic analyses of several Src family members have revealed critical roles for the SH3 and SH2 domains
in the down-regulation of the kinase domain. This review focuses on biological, biophysical, and computational studies that
reveal conformationally distinct active states within this unique kinase family.
Received 10 March 2008; received after revision 17 May 2008; accepted 21 May 2008 相似文献
1