全文获取类型
收费全文 | 351篇 |
免费 | 0篇 |
专业分类
系统科学 | 5篇 |
理论与方法论 | 1篇 |
现状及发展 | 12篇 |
研究方法 | 29篇 |
综合类 | 302篇 |
自然研究 | 2篇 |
出版年
2019年 | 1篇 |
2018年 | 1篇 |
2017年 | 1篇 |
2016年 | 1篇 |
2015年 | 1篇 |
2014年 | 1篇 |
2013年 | 4篇 |
2012年 | 24篇 |
2011年 | 34篇 |
2010年 | 6篇 |
2009年 | 1篇 |
2008年 | 15篇 |
2007年 | 32篇 |
2006年 | 25篇 |
2005年 | 41篇 |
2004年 | 48篇 |
2003年 | 57篇 |
2002年 | 45篇 |
2001年 | 1篇 |
2000年 | 6篇 |
1997年 | 1篇 |
1996年 | 1篇 |
1981年 | 2篇 |
1977年 | 1篇 |
1976年 | 1篇 |
排序方式: 共有351条查询结果,搜索用时 265 毫秒
1.
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants 总被引:2,自引:0,他引:2
Wellcome Trust Case Control Consortium;Australo-Anglo-American Spondylitis Consortium 《Nature genetics》2007,39(11):1329-1337
We have genotyped 14,436 nonsynonymous SNPs (nsSNPs) and 897 major histocompatibility complex (MHC) tag SNPs from 1,000 independent cases of ankylosing spondylitis (AS), autoimmune thyroid disease (AITD), multiple sclerosis (MS) and breast cancer (BC). Comparing these data against a common control dataset derived from 1,500 randomly selected healthy British individuals, we report initial association and independent replication in a North American sample of two new loci related to ankylosing spondylitis, ARTS1 and IL23R, and confirmation of the previously reported association of AITD with TSHR and FCRL3. These findings, enabled in part by increased statistical power resulting from the expansion of the control reference group to include individuals from the other disease groups, highlight notable new possibilities for autoimmune regulation and suggest that IL23R may be a common susceptibility factor for the major 'seronegative' diseases. 相似文献
2.
3.
Douglas A. Wilson Victoria Raish Alison Carr-Chellman 《Systemic Practice and Action Research》2017,30(3):277-293
The paper explores cinematic films as a pedagogical tool to promote critical thinking and student discussions in a doctoral-level learning, design, and technology seminar course at a major U.S. research university. These discussions focused on systemic change and systemic thinking concepts. The authors offer evidence from the literature that supports films’ power as a visual metaphor and neurocognitive stimulator to promote development of new perspectives in graduate students on case studies through articulation, reflection, and explanation of their thought processes on change and diffusion of innovation. There are theoretical, political, social, and technological issues that create tensions during any systemic change effort. The goal of using film in this seminar is to equip students with the requisite skills, theoretical frameworks, and interpersonal experiences needed to address these issues within organizations and communities. The change expected from systemic thinking is for students to think more deeply about the interconnectedness of systems and the importance of bottom-up change efforts that consider the perspective of all stakeholders. 相似文献
4.
5.
Academic accused of living on borrowed lines 总被引:1,自引:0,他引:1
6.
7.
8.
9.
10.