PDO血管内支架的制备及其径向压缩性能

以4种不同直径的聚对二氧环己酮(PDO)单丝为原料,采用手工编织的方法制备16种不同编织密度的血管内支架.对PDO单丝的力学性能、血管内支架的结构参数、径向压缩性能的测试方法和径向压缩性能进行试验研究.试验结果表明:采用PDO单丝手工编织的血管内支架的孔隙率符合选用要求;血管内支架的径向支撑力和弹性回复率随着单丝直径与编织密度的增加而增加,且单丝直径对血管内支架的径向压缩性能影响更显著.     

Radial Force Analysis of Polydioxanone Coronary Stent by Finite Element Method

Coronary stent is used to treat stenosis artery by recovering the luminal diameter of artery and maintaining the normal blood flow. The geometry of coronary stent is an important factor for the radial force. In this study,the relation between the radial force of stent and crown angle was discussed. The result showed that there was no particular rule between the radial force of stent and the crown angle. The maximum radial force of stent was obtained when the crown angle was 50. 04° and the minimum radial force was got when the crown angle was 75°.     

Evaluation of Relationship between the Geometry of Crown and Radial Force in a Polydioxanone Coronary Stent

Polydioxanone(PDS),one of the bioabsorbable materials for coronary stent,is catching eyes of researchers recently. When designing the geometry of the PDS coronary stent,the length and the height of the crown are quite important. However,rarely literatures have discussed the relationship between the two geometry parameters and the radial force of the bioabsorbable coronary stent. Therefore,a current effective tool of finite element method was applied in the evaluation of the relationship. By simulating 4 groups of models,it was obtained that the radial force of the coronary stent would not definitely increase with the rising value of Lcrownfrom 0. 8 mm to 2. 4mm. Meanwhile,Hcrownand radial force of the coronary stent had no linear relationship with each other.