Why the Afshar experiment does not refute complementarity

A modified version of Young's experiment by Shahriar Afshar demonstrates that, prior to what appears to be a “which-way” measurement, an interference pattern exists. Afshar has claimed that this result constitutes a violation of the Principle of Complementarity. This paper discusses the implications of this experiment and considers how Cramer's Transactional Interpretation easily accommodates the result. It is also shown that the Afshar experiment is analogous in key respects to a spin one-half particle prepared as “spin up along x”, subjected to a nondestructive confirmation of that preparation, and post-selected in a specific state of spin along z. The terminology “which-way” or “which-slit” is critiqued; it is argued that this usage by both Afshar and his critics is misleading and has contributed to confusion surrounding the interpretation of the experiment. Nevertheless, it is concluded that Bohr would have had no more problem accounting for the Afshar result than he would in accounting for the aforementioned pre- and post-selection spin experiment, in which the particle's preparation state is confirmed by a nondestructive measurement prior to post-selection. In addition, some new inferences about the interpretation of delayed choice experiments are drawn from the analysis.     

Sparse Bayesian vector autoregressions in huge dimensions

We develop a Bayesian vector autoregressive (VAR) model with multivariate stochastic volatility that is capable of handling vast dimensional information sets. Three features are introduced to permit reliable estimation of the model. First, we assume that the reduced-form errors in the VAR feature a factor stochastic volatility structure, allowing for conditional equation-by-equation estimation. Second, we apply recently developed global–local shrinkage priors to the VAR coefficients to cure the curse of dimensionality. Third, we utilize recent innovations to sample efficiently from high-dimensional multivariate Gaussian distributions. This makes simulation-based fully Bayesian inference feasible when the dimensionality is large but the time series length is moderate. We demonstrate the merits of our approach in an extensive simulation study and apply the model to US macroeconomic data to evaluate its forecasting capabilities.     

The quantum liar experiment in Cramer's transactional interpretation

Cramer's Transactional Interpretation (TI) is applied to the “quantum liar experiment” (QLE). It is shown how some apparently paradoxical features can be explained naturally, albeit nonlocally (since TI is an explicitly nonlocal interpretation, at least from the vantage point of ordinary spacetime). At the same time, it is proposed that in order to preserve the elegance and economy of the interpretation, it may be necessary to consider offer and confirmation waves as propagating in a “higher space” of possibilities.     

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

To identify rheumatoid arthritis risk loci in European populations, we conducted a meta-analysis of two published genome-wide association (GWA) studies totaling 3,393 cases and 12,462 controls. We genotyped 31 top-ranked SNPs not previously associated with rheumatoid arthritis in an independent replication of 3,929 autoantibody-positive rheumatoid arthritis cases and 5,807 matched controls from eight separate collections. We identified a common variant at the CD40 gene locus (rs4810485, P = 0.0032 replication, P = 8.2 x 10(-9) overall, OR = 0.87). Along with other associations near TRAF1 (refs. 2,3) and TNFAIP3 (refs. 4,5), this implies a central role for the CD40 signaling pathway in rheumatoid arthritis pathogenesis. We also identified association at the CCL21 gene locus (rs2812378, P = 0.00097 replication, P = 2.8 x 10(-7) overall), a gene involved in lymphocyte trafficking. Finally, we identified evidence of association at four additional gene loci: MMEL1-TNFRSF14 (rs3890745, P = 0.0035 replication, P = 1.1 x 10(-7) overall), CDK6 (rs42041, P = 0.010 replication, P = 4.0 x 10(-6) overall), PRKCQ (rs4750316, P = 0.0078 replication, P = 4.4 x 10(-6) overall), and KIF5A-PIP4K2C (rs1678542, P = 0.0026 replication, P = 8.8 x 10(-8) overall).     

Episodic evolution of pyrin in primates: human mutations recapitulate ancestral amino acid states

Familial Mediterranean fever (FMF; MIM 249100) is an autosomal recessive disease characterized by recurrent attacks of fever with synovial, pleural or peritoneal inflammation. The disease is caused by mutations in the gene encoding the pyrin protein. Human population studies have revealed extremely high allele frequencies for several different pyrin mutations, leading to the conclusion that the mutant alleles confer a selective advantage. Here we examine the ret finger protein (rfp) domain (which contains most of the disease-causing mutations) of pyrin during primate evolution. Amino acids that cause human disease are often present as wild type in other species. This is true at positions 653 (a novel mutation), 680, 681, 726, 744 and 761. For several of these human mutations, the mutant represents the reappearance of an ancestral amino acid state. Examination of lineage-specific dN/dS ratios revealed a pattern consistent with the signature of episodic positive selection. Our data, together with previous human population studies, indicate that selective pressures may have caused functional evolution of pyrin in humans and other primates.     

de Broglie Waves as the “Bridge of Becoming” Between Quantum Theory and Relativity

It is hypothesized that de Broglie’s ‘matter waves’ provide a dynamical basis for Minkowski spacetime in an antisubstantivalist or relational account. The relativity of simultaneity is seen as an effect of the de Broglie oscillation together with a basic relativity postulate, while the dispersion relation from finite rest mass gives rise to the differentiation of spatial and temporal axes. Thus spacetime is seen as not fundamental, but rather as emergent from the quantum level. A result by Solov’ev which demonstrates that time is not an applicable concept at the quantum level is adduced in support of this claim. Finally, it is noted that de Broglie waves can be seen as the “bridge of becoming” discussed by (2005).     

A Multi-Flow Information Flow Tracking Approach for Proving Quantitative Hardware Security Properties

Information Flow Tracking(IFT) is an established formal method for proving security properties related to confidentiality,integrity,and isolation.It has seen promise in identifying security vulnerabilities resulting from design flaws,timing channels,and hardware Trojans for secure hardware design.However,existing IFT methods tend to take a qualitative approach and only enforce binary security properties,requiring strict non-interference for the properties to hold while real systems usually allow a small amount of information flows to enable desirable interactions.Consequently,existing methods are inadequate for reasoning about quantitative security properties or measuring the security of a design in order to assess the severity of a security vulnerability.In this work,we propose two multi-flow solutions—multiple verifications for replicating existing IFT model and multi-flow IFT method.The proposed multi-flow IFT method provides more insight into simultaneous information flow behaviors and allows for proof of quantitative information flow security properties,such as diffusion,randomization,and boundaries on the amount of simultaneous information flows.Experimental results show that our method can be used to prove a new type of information flow security property with verification performance benefits.