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朱士群 《苏州大学学报(医学版)》1990,6(2):195-199
Effects of multiplicatioe noise in transient laser intensity are investigated theoretically. Analytic solutions are calculated through a reduced Fokker-Planck equation and the results with different pump parameters are discussed. 相似文献
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Jacobs KB Yeager M Zhou W Wacholder S Wang Z Rodriguez-Santiago B Hutchinson A Deng X Liu C Horner MJ Cullen M Epstein CG Burdett L Dean MC Chatterjee N Sampson J Chung CC Kovaks J Gapstur SM Stevens VL Teras LT Gaudet MM Albanes D Weinstein SJ Virtamo J Taylor PR Freedman ND Abnet CC Goldstein AM Hu N Yu K Yuan JM Liao L Ding T Qiao YL Gao YT Koh WP Xiang YB Tang ZZ Fan JH Aldrich MC Amos C Blot WJ Bock CH Gillanders EM Harris CC Haiman CA Henderson BE Kolonel LN Le Marchand L McNeill LH 《Nature genetics》2012,44(6):651-658
In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide association studies, we observed large chromosomal abnormalities in a subset of clones in DNA obtained from blood or buccal samples. We observed mosaic abnormalities, either aneuploidy or copy-neutral loss of heterozygosity, of >2 Mb in size in autosomes of 517 individuals (0.89%), with abnormal cell proportions of between 7% and 95%. In cancer-free individuals, frequency increased with age, from 0.23% under 50 years to 1.91% between 75 and 79 years (P = 4.8 × 10(-8)). Mosaic abnormalities were more frequent in individuals with solid tumors (0.97% versus 0.74% in cancer-free individuals; odds ratio (OR) = 1.25; P = 0.016), with stronger association with cases who had DNA collected before diagnosis or treatment (OR = 1.45; P = 0.0005). Detectable mosaicism was also more common in individuals for whom DNA was collected at least 1 year before diagnosis with leukemia compared to cancer-free individuals (OR = 35.4; P = 3.8 × 10(-11)). These findings underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases. 相似文献
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A C3Cl-type(bcc)-semi-infinite ferrimagnet with a single-ion uniaxial anisotropy and a magnetic impurity layer is considered through combining Green‘s function theory with the transfer-mairx method.The effect of the anisotropy term and the impurity layer on surface spin wave specirum is discussed.The influence of the impurity layer‘s distance from the surface or surface spin woves is also concerned. 相似文献
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