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1.
针对国内新近研制开发的细旦丙纶纤维,本文依据服装舒适性理论,运用常规客观测试方法,对细旦丙纶针织物的液态水传递能力、液态水保持能力、透气性能,放湿干燥性能进行了探讨,最后用灰色聚类判别分析法进行了综合评价。  相似文献   
2.
What’s new in the renin-angiotensin system?   总被引:6,自引:0,他引:6  
The angiotensin AT(4) receptor was originally defined as the specific, high-affinity binding site for the hexapeptide angiotensin IV (Ang IV). Subsequently, the peptide LVV-hemorphin 7 was also demonstrated to be a bioactive ligand of the AT(4) receptor. Central administration of Ang IV, its analogues or LVV-hemorphin 7 markedly enhance learning and memory in normal rodents and reverse memory deficits observed in animal models of amnesia. The AT(4) receptor has a broad distribution and is found in a range of tissues, including the adrenal gland, kidney, lung and heart. In the kidney Ang IV increases renal cortical blood flow and decreases Na(+) transport in isolated renal proximal tubules. The AT(4) receptor has recently been identified as the transmembrane enzyme, insulin-regulated membrane aminopeptidase (IRAP). IRAP is a type II integral membrane spanning protein belonging to the M1 family of aminopeptidases and is predominantly found in GLUT4 vesicles in insulin-responsive cells. Three hypotheses for the memory-potentiating effects of the AT(4) receptor/IRAP ligands, Ang IV and LVV-hemorphin 7, are proposed: (i) acting as potent inhibitors of IRAP, they may prolong the action of endogenous promnestic peptides; (ii) they may modulate glucose uptake by modulating trafficking of GLUT4; (iii) IRAP may act as a receptor, transducing the signal initiated by ligand binding to its C-terminal domain to the intracellular domain that interacts with several cytoplasmic proteins.  相似文献   
3.
Mutations or rearrangements in the gene encoding the receptor tyrosine kinase RET result in Hirschsprung disease, cancer and renal malformations. The standard model of renal development involves reciprocal signaling between the ureteric bud epithelium, inducing metanephric mesenchyme to differentiate into nephrons, and metanephric mesenchyme, inducing the ureteric bud to grow and branch. RET and GDNF (a RET ligand) are essential mediators of these epithelial-mesenchymal interactions. Vitamin A deficiency has been associated with widespread embryonic abnormalities, including renal malformations. The vitamin A signal is transduced by nuclear retinoic acid receptors (RARs). We previously showed that two RAR genes, Rara and Rarb2, were colocalized in stromal mesenchyme, a third renal cell type, where their deletion led to altered stromal cell patterning, impaired ureteric bud growth and downregulation of Ret in the ureteric bud. Here we demonstrate that forced expression of Ret in mice deficient for both Rara and Rarb2 (Rara(-/-)Rarb2(-/-)) genetically rescues renal development, restoring ureteric bud growth and stromal cell patterning. Our studies indicate the presence of a new reciprocal signaling loop between the ureteric bud epithelium and the stromal mesenchyme, dependent on Ret and vitamin A. In the first part of the loop, vitamin-A-dependent signals secreted by stromal cells control Ret expression in the ureteric bud. In the second part of the loop, ureteric bud signals dependent on Ret control stromal cell patterning.  相似文献   
4.
讨论一个带有齐次Neumann边界条件的强耦合捕食模型,给出了非常数正解的存在性.  相似文献   
5.
主要考虑了一类形变Schr(o)dinger-Virasoro型李代数L的中间序列模,给出了此类模的完全分类.  相似文献   
6.
Removal of toxic substances from the blood depends on patent connections between the kidney, ureters and bladder that are established when the ureter is transposed from its original insertion site in the male genital tract to the bladder. This transposition is thought to occur as the trigone forms from the common nephric duct and incorporates into the bladder. Here we re-examine this model in the context of normal and abnormal development. We show that the common nephric duct does not differentiate into the trigone but instead undergoes apoptosis, a crucial step for ureter transposition controlled by vitamin A-induced signals from the primitive bladder. Ureter abnormalities occur in 1-2% of the human population and can cause obstruction and end-stage renal disease. These studies provide an explanation for ureter defects underlying some forms of obstruction in humans and redefine the current model of ureter maturation.  相似文献   
7.
ROS 作为信息分子是生命科学研究中继发现 NO 是信息分子后的又一重要事件。探索了外源性 ROS(H_2O_2)对人中性粒细胞(Np)呼吸爆发产物 O_2水平的影响,结果表明外源性 H_2O_2对 Np呼吸爆发水平有反馈调节作用。  相似文献   
8.
根据《仪器分析》实验课程的实际情况,探讨了用气质联用仪外标法进行定量分析的实验教学.介绍了气质联用仪的工作原理和基本构造等相关知识.通过该实验课程的学习,使学生掌握气质联用仪的基本操作,总结各种定量计算方法,学会特征离子的选择技巧,从而提高学生对实验的学习兴趣,锻炼学生分析问题、解决问题的能力.  相似文献   
9.
分别制备合成了碳载5-单羧基-10,15,20-三苯基钴卟啉(CoMCP)、铁卟啉(FeMCP)、锰卟啉(MnMCP)、铜卟啉(CuMCP)和镍卟啉(NiMCP)复合催化剂,并通过线性电势扫描法研究该复合材料对氧还原的电催化性能和抗甲醇能力.结果表明:MnMCP对氧还原有较高的电催化活性,其氧还原起始电位为0.513V,催化性能最好;其他金属复合材料按照CoMCP,FeMCP,CuMCP顺序降低,而NiMCP的起始电位仅为0.198V,对氧还原的催化性能相对最弱;在抗甲醇性能测试中,CoMCP,FeMCP,CuMCP,NiMCP的氧还原起始电位正移,具有较好的抗甲醇能力.  相似文献   
10.
在彩色可视传感阵列传统处理方法中,存在着数据量大,人工分析困难、种类浓度识别难以同一次实现等问题,针对这些问题,考虑到同类气体饱和响应阵列点位置一致性的特点,提出一种彩色可视阵列基元匹配快速定量识别算法。该算法首先采用设置经验阈值消除冗余量,进行去噪和特征提取,减少人工分析量;然后进行基于二值化基元图模板匹配的定量分析种类识别,减少计算量,增加气体识别效率和精度;最后,综合模糊逻辑和神经网络2种人工智能方法的优点,建立彩色传感阵列气体浓度识别的自适应模糊推理系统。算法优势在于将不同气体的种类和浓度检测分开进行,解决了种类、浓度同时识别时可能出现特征数据交叉感染导致错误识别的问题。基元模板匹配分析结果显示,氨气、氯气和二氧化硫3种气体分类识别结果准确率达100%,利用模糊神经网络方法对氨气浓度识别率准确度较高,误差在5%以内。  相似文献   
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